Evidence map›Paper›PMID 42589015›Full record

ArticleAnimals : an open access journal from MDPI2026

Proteomic Analysis of Dairy Cows with Persistent Subclinical Hypocalcemia.

Yunlong Bai, Junbo Hu, Jingyi Liu, Xudong Sun, Chuang Xu, Jiajing Liu, Xiaochen Jia, Yu Yang, Lianying Wang, Guang Shao and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yunlong BaiCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agriculture University, Daqing 163319, China.
Junbo HuCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agriculture University, Daqing 163319, China.
Jingyi LiuCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agriculture University, Daqing 163319, China.
Xudong SunCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agriculture University, Daqing 163319, China.ORCID 0000-0001-5976-8960
Chuang XuCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-0377-1439
Jiajing LiuCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Xiaochen JiaHeilongjiang Mudanjiang Agricultural Reclamation Jiangjun Dairy Cow Breeding Professional Cooperative, Jixi 158100, China.
Yu YangJiamusi Animal Disease Prevention and Control Center, Jiamusi 154000, China.
Lianying WangDaqing Agricultural and Rural Social Undertakings Service Center, Daqing 163319, China.
Guang ShaoBranch of Animal Husbandry and Veterinary Sciences, Heilongjiang Academy of Agricultural Sciences, Qiqihar 161000, China.
Qitao ZhuInner Mongolia Shengmu High-Tech Animal Husbandry Co., Ltd., Hohhot 010111, China.
Caixia RuXi'an Caotan Animal Husbandry Co., Ltd., Xi'an 710018, China.
Mengjiao WangHospital of Heilongjiang Bayi Agricultural University, Daqing 163319, China.
Cheng XiaCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agriculture University, Daqing 163319, China.ORCID 0000-0002-6752-5659
Yuxi SongCollege of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agriculture University, Daqing 163319, China.

Funding

Heilongjiang Province "Double First-Class" Discipline Collaborative Innovation Achievement Project LJGXCG2025-P36Heilongjiang Provincial Natural Science Foundation Joint Project for University (Institute)-Enterprise Cooperation JJ2025XQ0075National Natural Science Foundation of China 32573447
6 · The paper itself

Abstract

To delineate the serum proteomic profile of persistent subclinical hypocalcemia (pSCH) in periparturient dairy cows, elucidate its molecular pathogenesis, and provide a theoretical basis for early warning and precision prevention and control, we selected 12 Holstein dairy cows of similar age (2.92 ± 0.12 years), parity (1.56 ± 0.21), body condition score (BCS) (2.84 ± 0.04), milk yield (26.81 ± 0.22 kg/d), and day in milk (DIM) (6.60 ± 0.24 d) and no significant between-group differences as experimental animals. Based on serum calcium concentrations on postpartum days 1 to 4 and clinical presentation, the cows were divided into a healthy control group (serum calcium > 1.77 mmol/L on day 1 and >2.20 mmol/L on day 4 postpartum,

Indexed as

4D-DIA quantitative proteomicsdairy cowspersistent subclinical hypocalcemiaproteomics

Identifiers

PMID42589015
PMCPMC13465629

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.