Evidence map›Paper›PMID 42589189›Full record

ReviewBiology2026

Multi-Omics Biomarkers in Head and Neck Squamous Cell Carcinoma: Biological Insights and Clinical Translation: A Narrative Review.

Lucas de Araújo Albuquerque, Lilianny Querino Rocha de Oliveira, Déborah Gondim Lambert Moreira, Glória Maria de França, Roseana de Almeida Freitas, José Roberto Viana Silva, Everton Freitas de Morais

Abstract readReview
In one paragraph

Review in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucas de Araújo AlbuquerqueLaboratory of Biotechnology and Physiology of Reproduction, Federal University of Ceara, Sobral 62041-040, CE, Brazil.
Lilianny Querino Rocha de OliveiraLaboratory of Nutrient and Tissue Repair (LABNUTRE), School of Applied Sciences, University of Campinas, Limeira 13484-350, SP, Brazil.
Déborah Gondim Lambert MoreiraDepartment of Oral Pathology, Federal University of Rio Grande do Norte, Natal 59056-000, RN, Brazil.
Glória Maria de FrançaProfessional Master's Program in Health Research, Cesmac University Center, Maceió 57051-160, AL, Brazil.ORCID 0000-0002-0483-6601
Roseana de Almeida FreitasDepartment of Oral Pathology, Federal University of Rio Grande do Norte, Natal 59056-000, RN, Brazil.
José Roberto Viana SilvaLaboratory of Biotechnology and Physiology of Reproduction, Federal University of Ceara, Sobral 62041-040, CE, Brazil.ORCID 0000-0002-5970-6177
Everton Freitas de MoraisLaboratory of Biotechnology and Physiology of Reproduction, Federal University of Ceara, Sobral 62041-040, CE, Brazil.ORCID 0000-0002-2173-7672

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSCC) continues to be an important health problem worldwide, with high morbidity and mortality and considerable biological variability among tumors. Although clinicopathological features remain essential in clinical practice, they do not fully explain differences in tumor behavior or treatment response. The growing availability of molecular data has therefore increased interest in multi-omics strategies for HNSCC. Genomic, transcriptomic, epigenomic, proteomic, and metabolomic analyses provide different, but complementary, views of tumor biology. Genomic alterations, including recurrent changes in

Indexed as

biomarkersmolecular heterogeneitymulti-omicssquamous cell carcinomatumor microenvironment

Identifiers

PMID42589189
PMCPMC13463855

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.