Evidence mapPaperPMID 42589253Full record

ArticleInternational journal of molecular sciences2026

Integrative Metabolomic Evidence of Bioactive Food-Derived Compounds Targeting Alzheimer's Disease: A Cross-Study Analysis in

Tamara Y Forbes-Hernández, Carmen Quiles-Ramírez, Francesca Giampieri, Justyna Godos, Giuseppe Grosso, Carmen L Rodríguez-Velasco, Jianbo Xiao, Maowen Ding, Maurizio Battino, Lorenzo Rivas-García and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tamara Y Forbes-HernándezDepartimento di Scienze Biomediche, University of Cagliari, Cittadella Universitaria-S.S. 554 Bivio per Sestu, 09042 Monserrato, Italy.ORCID 0000-0001-7021-9276
Carmen Quiles-RamírezAndalusian Research Institute in Data Science and Computational Intelligence (DaSCI), University of Granada, 18071 Granada, Spain.
Francesca GiampieriDipartimento di Scienze Cliniche Specialistiche, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy.ORCID 0000-0002-8151-9132
Justyna GodosDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-5809-5706
Giuseppe GrossoDepartment of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-3930-5285
Carmen L Rodríguez-VelascoResearch Group on Food, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.
Jianbo XiaoDepartment of Analytical and Food Chemistry, Faculty of Science, University of Vigo, 32004 Ourense, Spain.ORCID 0000-0003-3311-770X
Maowen DingDepartment of Physiology, Institute of Nutrition and Food Technology "José Mataix Verdú", Biomedical Research Centre, University of Granada, Avda. del Conocimiento s.n, 18100 Armilla, Spain.
Maurizio BattinoDipartimento di Scienze Cliniche Specialistiche, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy.ORCID 0000-0002-7250-1782
Lorenzo Rivas-GarcíaDepartment of Physiology, Institute of Nutrition and Food Technology "José Mataix Verdú", Biomedical Research Centre, University of Granada, Avda. del Conocimiento s.n, 18100 Armilla, Spain.ORCID 0000-0002-0413-8432
Cristina Sánchez-GonzálezDepartment of Physiology, Institute of Nutrition and Food Technology "José Mataix Verdú", Biomedical Research Centre, University of Granada, Avda. del Conocimiento s.n, 18100 Armilla, Spain.ORCID 0000-0002-1044-4858

Funding

Government of Spain PID2019-106778RB-I00Universidad de Granada Visiting Scholars 2022
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a major neurodegenerative condition with limited treatment options. Applications of food-derived products rich in bioactive compounds have emerged as promising strategies, yet comparative evidence across different matrices remains scarce. Here, we present an integrative metabolomic analysis of eleven food extracts previously tested in

Indexed as

Alzheimer DiseaseCaenorhabditis elegansMetabolomeMetabolomicsAmyloid beta-PeptidesAnimalsAntioxidantsCholinesterase InhibitorsDisease Models, AnimalFlavonoidsNeuroprotective AgentsOxidative StressPolyphenolsAmyloid beta-PeptidesAntioxidantsCholinesterase InhibitorsFlavonoidsNeuroprotective AgentsPolyphenolsacetylcholinesteraseAlzheimer’s diseaseantioxidantsparalysisphytochemistrytau protein

Identifiers

PMID42589253
PMCPMC13467014

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.