Evidence map›Paper›PMID 42589307›Full record

ArticleInternational journal of molecular sciences2026

Nanostructured Tin- and Titanium-Based Chemoresistive Sensors for Detecting Volatile Fingerprints from Colorectal Cancer Biopsies and Cell Lines.

Michele Astolfi, Martina Masin, Antonio Anfuso, Cesare Malagù, Gabriele Anania, Mascia Benedusi, Giuseppe Valacchi, Giorgio Rispoli

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michele AstolfiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-3578-0946
Martina MasinDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Antonio AnfusoDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0009-0000-2950-8500
Cesare MalagùDepartment of Physics and Earth Sciences, University of Ferrara, Via G. Saragat 1, 44121 Ferrara, Italy.ORCID 0000-0002-8362-5289
Gabriele AnaniaDepartment of Medical Sciences, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0001-9255-3312
Mascia BenedusiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.
Giuseppe ValacchiDepartment of Environmental and Prevention Sciences, University of Ferrara, C.so Ercole I d'Este 32, 44121 Ferrara, Italy.ORCID 0000-0002-8792-0947
Giorgio RispoliDepartment of Neuroscience and Rehabilitation, University of Ferrara, Via L. Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-9390-5620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer represents a global health burden, being the third most frequently diagnosed cancer worldwide, accounting for about 1.9 million new cases annually, and the second leading cause of cancer-related deaths. This highlights the need for innovative and effective methods for cancer detection, improving current diagnostic approaches. In this feasibility study, two nanostructured chemoresistive gas sensors based on tin oxide-titanium oxide composites were selected to detect the metabolic patterns associated with human healthy and colorectal cancer tissues, collected from 26 patients. To further validate the biopsy-derived results, the sensors were tested on two colorectal cancer-derived cell lines, namely Caco-2 and RKO. Both sensors were able to discriminate between healthy and tumor samples by comparing the mean sensor responses, using the paired

Indexed as

Biosensing TechniquesColorectal NeoplasmsNanostructuresTin CompoundsTitaniumVolatile Organic CompoundsBiopsyCaco-2 CellsCell Line, TumorFemaleHumansstannic oxideTin CompoundsTitaniumtitanium dioxideVolatile Organic Compoundscancerchemoresistivitycolorectal cancerfingerprintgas sensorsnanostructurespotential barrierssensitivitysensor deviceVOCs

Identifiers

PMID42589307
PMCPMC13466127

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.