Observational studyInternational journal of molecular sciences2026
Differential Regulation of Inflammatory and Pro-Resolving Lipid Mediators in Chronic Coronary Syndrome Across Cardiometabolic Phenotypes.
Observational study in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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17 authors.
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Abstract
Chronic coronary syndrome (CCS) is characterized by persistent low-grade inflammation and impaired resolution of inflammatory responses within the vascular wall. Specialized pro-resolving mediators (SPMs), including resolvins and maresins, play an essential role in terminating inflammation and restoring tissue homeostasis. This prospective observational study included 83 patients hospitalized due to stable angina or angina-equivalent symptoms. Serum concentrations of leukotriene B4 (LTB4), maresin-1 (MaR1), resolvin E1 (RvE1), resolvin D1 (RvD1), and prostaglandin E2 (PGE2) were determined using enzyme-linked immunosorbent assays. Associations between mediator concentrations and clinical characteristics-including sex, age, and body mass index (BMI)-were analyzed using nonparametric statistical tests with false-discovery-rate correction. Women, patients ≥65 years of age, and individuals with BMI ≥ 30 kg/m
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