Evidence map›Paper›PMID 42589374›Full record

ArticleInternational journal of molecular sciences2026

Proteomic Analysis of TCGA Data Reveals Limited Prognostic Value of p53 but Suggests BAX as a Potential Survival Marker in Cervical Carcinoma.

Sebastian M Toennießen-Klein, Dennis Rangno, Abhirami Sunil, Maria Bozko, Przemyslaw Bozko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastian M Toennießen-KleinDepartment of Internal Medicine I, University Hospital Tübingen, 72076 Tübingen, Germany.
Dennis RangnoDepartment of Internal Medicine I, University Hospital Tübingen, 72076 Tübingen, Germany.
Abhirami SunilThe M3 Research Center, Eberhard-Karls Universität Tübingen, 72076 Tübingen, Germany.ORCID 0009-0004-5683-2743
Maria BozkoInstitute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, 02-106 Warsaw, Poland.
Przemyslaw BozkoDepartment of Internal Medicine I, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0001-8126-3686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical carcinoma is predominantly driven by high-risk human papillomavirus (HPV) infection, in which functional inactivation of p53 occurs mainly through viral oncoproteins rather than mutations in the

Indexed as

bcl-2-Associated X ProteinBiomarkers, TumorProteomicsTumor Suppressor Protein p53Uterine Cervical NeoplasmsCyclin-Dependent Kinase Inhibitor p21FemaleHuman Papillomavirus VirusesHumansMutationPrognosisBAX protein, humanbcl-2-Associated X ProteinBiomarkers, TumorCyclin-Dependent Kinase Inhibitor p21TP53 protein, humanTumor Suppressor Protein p53Cancer Genome Atlascervical cancerdiagnostic importanceHPVp53patient survival

Identifiers

PMID42589374
PMCPMC13466968

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.