Evidence map›Paper›PMID 42589451›Full record

ReviewInternational journal of molecular sciences2026

The Repair Manual of a Fruit Fly Brain.

Isabella Peetz, Ayelet Blum, Shawn Ahern-Djamali, Grace Boekhoff-Falk

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Isabella PeetzDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705, USA.ORCID 0009-0006-8631-5354
Ayelet BlumDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705, USA.
Shawn Ahern-DjamaliDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705, USA.
Grace Boekhoff-FalkDepartment of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI 53705, USA.ORCID 0000-0002-9877-8309

Funding

Neurogenesis in the adult Drosophila brainR01NS126444 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GRACE E BOEKHOFF-FALK · 2023 to 2026
$1.5M
NINDS NIH HHS R01 NS126444
6 · The paper itself

Abstract

The brain is a complex organ; its diverse functions and plasticity correspond with an intricate structure. Integrating sensory inputs with internal physiological states, the brain orchestrates balance, posture, movement, speech, emotions, the creation of memories, and the ability to learn. Whether due to trauma, disease, or stroke, disruptions to brain architecture have long-lasting consequences for a person's physical, behavioral, emotional, and cognitive health. Comparative studies using model systems to identify meaningful therapies and treatments are critical to elucidate the mechanisms underlying regenerative processes in the brain. This review focuses on the model organism

Indexed as

BrainDrosophila melanogasterNerve RegenerationAnimalsHumansNeurogenesisDrosophilagliogenesisneural regenerationneurogenesis

Identifiers

PMID42589451
PMCPMC13467525

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.