Evidence map›Paper›PMID 42589582›Full record

ArticleInternational journal of molecular sciences2026

Pre-Dialysis Serum Myostatin Concentration Is Independently Associated with Intradialytic Muscle Cramps in Hemodialysis Patients.

Agnieszka Makowka, Ewa Pawlowicz Szlarska, Gabriela Kot, Agata Wrobel, Michal Nowicki

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agnieszka MakowkaDepartment of Nephrology, Hypertension, Transplantation and Internal Medicine, Central University Hospital, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.
Ewa Pawlowicz SzlarskaDepartment of Nephrology, Hypertension, Transplantation and Internal Medicine, Central University Hospital, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.
Gabriela KotFaculty of Medicine, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.
Agata WrobelFaculty of Medicine, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.
Michal NowickiDepartment of Nephrology, Hypertension, Transplantation and Internal Medicine, Central University Hospital, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.ORCID 0000-0002-0823-5440

Funding

Medical University of Lodz This research was supported by institutional funds from the Department of Nephrology, Medical University of Lodz.
6 · The paper itself

Abstract

Muscle cramps are among the most common acute complications of hemodialysis (HD), often occurring even in the absence of electrolyte disturbances. Most cramps are painful and may cause patients to fear future dialysis sessions. We hypothesized that susceptibility to muscle cramps may be related to impaired skeletal muscle myokine secretion. No significant differences in pre-dialysis myokine levels were observed between patients with and without muscle cramps (myostatin 36.2 vs. 86.9 (

Indexed as

Muscle CrampMyostatinRenal DialysisAgedBiomarkersFemaleFibronectinsHumansInterleukin-6MaleMiddle AgedMyokinesBiomarkersFibronectinsFNDC5 protein, humanInterleukin-6MSTN protein, humanMyokinesMyostatinhemodialysismuscle crampsmyokinesmyostatin

Identifiers

PMID42589582
PMCPMC13467124

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.