ArticleInternational journal of molecular sciences2026
Inflammatory Factors Associated with Late-Life Depressive Symptoms in Oldest-Old Patients with Type 2 Diabetes.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
While many studies indicate a bidirectional relationship between type 2 diabetes (T2DM) and depression, its precise nature remains unclear. The aim of the study was to determine the levels of inflammatory markers in oldest-old patients with diabetes and depressive symptoms and identify the risk factors associated with late-life depressive symptoms. In total, 195 participants with diabetes, aged 85 and above, were screened for depressive symptoms using the 30-item Geriatric Depression Scale (GDS-30). Clinical and biochemical data were also collected. Serum levels of inflammatory markers were measured via enzyme-linked immunosorbent assay (ELISA). Serum levels of TNF-α, IL-1β, and IL-6 were increased in individuals with depression and correlated with each other as well as with HbA
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