ArticleInternational journal of molecular sciences2026
Time-Resolved Metabolomics Reveals Distinct, Cell- and Variety-Dependent Profiles of Prostanoids in Melanoma Cells Exposed to Fruit Extracts from
Łukasz Lewandowski, Małgorzata Krzystek-Korpacka, Daria Mykhailova, Martyna Korbecka, Michał Bryk, Mariusz Fleszar, Paulina Fortuna, Alicja Z Kucharska, Tomasz Sozański, Jolanta Zalejska-Fiolka and 3 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Łukasz LewandowskiDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0002-7624-631X Małgorzata Krzystek-KorpackaDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Daria MykhailovaDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0009-0001-8563-9625 Martyna KorbeckaDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0001-9507-7067 Michał BrykDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Alicja Z KucharskaDepartment of Fruit, Vegetable and Plant Nutraceutical Technology, Wroclaw University of Environmental and Life Sciences, J. Chełmońskiego 37, 51-630 Wroclaw, Poland.ORCID 0000-0002-2172-0408 Tomasz SozańskiDepartment of Preclinical Sciences, Pharmacology and Medical Diagnostics, Wroclaw University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wroclaw, Poland.ORCID 0000-0003-1722-3190 Jolanta Zalejska-FiolkaDepartment of Biochemistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 40-055 Katowice, Poland.ORCID 0000-0002-3879-6548 Karolina MosnaOmics Research Center, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Wioleta SzewczakOmics Research Center, Wroclaw Medical University, 50-368 Wroclaw, Poland.
Iwona Bednarz-MisaDepartment of Biochemistry and Immunochemistry, Faculty of Medicine, Wroclaw Medical University, 50-368 Wroclaw, Poland.ORCID 0000-0001-7244-2017 Funding
Wroclaw Medical University SUBK.A412.23.070
6 · The paper itselfAbstract
Chronic inflammation and cyclooxygenase (COX)-2-mediated prostanoid signaling contribute to melanoma progression, yet their modulation by natural products remains poorly defined. We examined the effects of dogwood fruit extracts-Japanese cornel (
Indexed as
CornusFruitMelanomaMetabolomicsPlant ExtractsProstaglandinsCell Line, TumorCyclooxygenase 2HumansPilot ProjectsCyclooxygenase 2Plant ExtractsProstaglandinsanthocyaninsbioactive phytochemicalscyclooxygenase-2GAMLSS (hierarchical modeling)iridoid glycosidesprostaglandins
Identifiers
PMID42589636
PMCPMC13467092
What Socratic holds
Textmetadata
Read underepoch 390