Evidence map›Paper›PMID 42589644›Full record

ArticleInternational journal of molecular sciences2026

Doxorubicin-Incorporated Nanoparticles Composed of Ce6-Conjugated Hyaluronic Acid-

Tae Hyeon Kim, Kyung-Jin Oh, Myeong Yoo Park, Ilkeun Kong, Jaewon Jo, Young-Ju Lee, Hyo-Young Lee, Doug-Hoon Kim, Jinsu Park, Jae-Woon Nah and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tae Hyeon KimDivision of Animal Science, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0002-2544-8608
Kyung-Jin OhDepartment of Urology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.ORCID 0000-0001-5611-7994
Myeong Yoo ParkDepartment of Urology, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju 61469, Republic of Korea.
Ilkeun KongDivision of Animal Science, Gyeongsang National University, Jinju 52828, Republic of Korea.ORCID 0000-0001-5567-1088
Jaewon JoGwangju Center, Korea Basic Science Institute, Gwangju 61186, Republic of Korea.
Young-Ju LeeGwangju Center, Korea Basic Science Institute, Gwangju 61186, Republic of Korea.
Hyo-Young LeeDepartment of Radiological Science, Dong-Eui University, Pusan 47340, Republic of Korea.
Doug-Hoon KimDepartment of Optometry, Masan University, Changwon 51217, Republic of Korea.
Jinsu ParkThe Korean Association for the Industrial Technology Security, Seoul 06732, Republic of Korea.
Jae-Woon NahKittolife, Pyeongtaek-si 17749, Republic of Korea.
Young-Il JeongInstitute of Well-Aging Medicare & Chosun University G-LAMP Project Group, Chosun University, Gwangju 61452, Republic of Korea.ORCID 0000-0002-9832-4331

Funding

Chonnam National University Hospital BCRI22045
6 · The paper itself

Abstract

Oxidative stress in the tumor microenvironment, which is its own intrinsic property, is frequently utilized to deal with the drug-targeting issue in the nanoparticle drug delivery system. For this purpose, reactive oxygen species (ROS)-sensitive nanoparticles encapsulating doxorubicin (DOX) and chlorin e6 (Ce6) were synthesized for treatment of MDA-MB-231 breast cancer cells. Hyaluronic acid (HA) with a reductive end was conjugated with methoxy poly(ethylene glycol) (PEG) using thioketal diamine (ThdNH

Indexed as

Breast NeoplasmsDoxorubicinDrug Resistance, NeoplasmHyaluronic AcidNanoparticlesPolyethylene GlycolsPorphyrinsAnimalsAntibiotics, AntineoplasticCell Line, TumorChlorophyllidesDrug CarriersFemaleHumansMDA-MB-231 CellsMiceAntibiotics, AntineoplasticChlorophyllidesDoxorubicinDrug CarriersHyaluronic AcidphytochlorinPolyethylene GlycolsPorphyrinsReactive Oxygen Specieschemotherapydrug-resistant cancernanoparticlesphotodynamic therapyreactive oxygen speciestumor targeting

Identifiers

PMID42589644
PMCPMC13466280

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.