Evidence mapPaperPMID 42589658Full record

ArticleInternational journal of molecular sciences2026

Multi-Targeted Neuroprotection by

Kishore K Kumaree, Clerance Su Yee Cheong, Kanika Verma, Kartina Nadyani, Nureesun Mahamud, Pornpimol Mahamad, Tewin Tencomnao, Anchalee Prasansuklab, James M Brimson

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kishore K KumareeCollege of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-0693-6366
Clerance Su Yee CheongCenter of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age NatChula), Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-5968-8936
Kanika VermaCenter of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age NatChula), Chulalongkorn University, Bangkok 10330, Thailand.
Kartina NadyaniCenter of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age NatChula), Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0009-0002-6142-6702
Nureesun MahamudThe Halal Science Center, Chulalongkorn University, Bangkok 10330, Thailand.
Pornpimol MahamadThe Halal Science Center, Chulalongkorn University, Bangkok 10330, Thailand.
Tewin TencomnaoCenter of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age NatChula), Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-4177-2165
Anchalee PrasansuklabCollege of Public Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0001-8884-3077
James M BrimsonCenter of Excellence on Natural Products for Neuroprotection and Anti-Ageing (Neur-Age NatChula), Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-2074-8262

Funding

Thailand Science Research and Innovation Fund, Chulalongkorn University HEA_FF_68_155_3700_013
6 · The paper itself

Abstract

Cisplatin is an effective platinum-based chemotherapeutic agent used to treat a variety of cancers. However, its clinical utility is limited by dose-dependent neurotoxicity, yet no approved neuroprotective strategy currently exists. Our integrated cellular, metabolic, and in vivo approaches unraveled the neuroprotective potential of

Indexed as

ArecaCaenorhabditis elegansCisplatinNeuroprotective AgentsNeurotoxicity SyndromesPlant ExtractsAnimalsAntineoplastic AgentsAntioxidantsCell SurvivalHumansMetabolomicsMiceNeuronsReactive Oxygen SpeciesAntineoplastic AgentsAntioxidantsCisplatinNeuroprotective AgentsPlant ExtractsReactive Oxygen Speciesareca nutC. eleganschemotherapy-associated neuropathyHT22metabolomicsplatinum-based drugs

Identifiers

PMID42589658
PMCPMC13467248

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.