Evidence map›Paper›PMID 42589687›Full record

ArticleInternational journal of molecular sciences2026

Computationally Generated Plant-Derived Berberine-Based Hybrid Compounds as Potential Dual Binders to

Julio César Robles-Romero, Jael Quintero-Vargas, Karen Ochoa Lara, Mario Alberto Leyva-Peralta, Milagros Aguilar-Martínez, Luis Eduardo Hernandez-Dominguez, Francisco José Palacios-Can, Simon Bernard Iloki-Assagna, Rodrigo Said Razo-Hernández, Juan Carlos Gálvez-Ruiz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julio César Robles-RomeroDepartamento de Ciencias Químico-Biológicas, Universidad de Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo C.P. 83000, Sonora, Mexico.
Jael Quintero-VargasDepartamento de Ciencias de la Salud, Universidad de Sonora, Blvd. Bordo Nuevo s/n, Ciudad Obregón C.P. 85039, Sonora, Mexico.ORCID 0000-0002-7471-6269
Karen Ochoa LaraDepartamento de Investigación en Polímeros y Materiales, Universidad de Sonora, Rosales y Encinas s/n, Hermosillo C.P. 83000, Sonora, Mexico.ORCID 0000-0002-5271-2718
Mario Alberto Leyva-PeraltaDepartamento de Ciencias Químico Biológicas y Agropecuarias, Universidad de Sonora, Avenida K s/n, Caborca C.P. 83600, Sonora, Mexico.ORCID 0000-0003-4335-3917
Milagros Aguilar-MartínezDepartamento de Ciencias Químico Biológicas y Agropecuarias, Universidad de Sonora, Avenida K s/n, Caborca C.P. 83600, Sonora, Mexico.
Luis Eduardo Hernandez-DominguezLaboratorio de Quimioinformática y Diseño de Fármacos, Centro de Investigación en Dinámica Celular (CIDC), Instituto de Investigación en Ciencias Básicas y Aplicadas (IICBA), Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca C.P. 62209, Morelos, Mexico.
Francisco José Palacios-CanLaboratorio de Quimioinformática y Diseño de Fármacos, Centro de Investigación en Dinámica Celular (CIDC), Instituto de Investigación en Ciencias Básicas y Aplicadas (IICBA), Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca C.P. 62209, Morelos, Mexico.ORCID 0000-0002-8162-5269
Simon Bernard Iloki-AssagnaDepartamento de Ciencias Químico-Biológicas, Universidad de Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo C.P. 83000, Sonora, Mexico.ORCID 0000-0002-2058-5881
Rodrigo Said Razo-HernándezLaboratorio de Quimioinformática y Diseño de Fármacos, Centro de Investigación en Dinámica Celular (CIDC), Instituto de Investigación en Ciencias Básicas y Aplicadas (IICBA), Universidad Autónoma del Estado de Morelos, Av. Universidad No. 1001, Cuernavaca C.P. 62209, Morelos, Mexico.ORCID 0000-0002-9716-9376
Juan Carlos Gálvez-RuizDepartamento de Ciencias Químico-Biológicas, Universidad de Sonora, Blvd. Luis Encinas y Rosales s/n, Hermosillo C.P. 83000, Sonora, Mexico.ORCID 0000-0002-4035-313X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsBerberineCytoskeletal ProteinsFatty Acid Synthase, Type IIStaphylococcus aureusLigandsMicrobial Sensitivity TestsMolecular Docking SimulationProtein BindingQuantitative Structure-Activity RelationshipAnti-Bacterial AgentsBacterial ProteinsBerberineCytoskeletal ProteinsFatty Acid Synthase, Type IIFtsZ protein, BacteriaLigandsberberineFabIFtsZhybrid compoundslipophilic acidsmultitarget approach

Identifiers

PMID42589687
PMCPMC13467142

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.