Evidence map›Paper›PMID 42589714›Full record

ArticleInternational journal of molecular sciences2026

In Vitro and In Silico Insights into the Antiproliferative Activity of Sesquiterpenes from

Maria Michela Salvatore, Marco Masi, Muhammad Suleman, Haritha Kalath, Mai M Karousa, Maha M Ayoub, Abdullah A Shaito, Anna Andolfi

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria Michela SalvatoreDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.ORCID 0000-0001-8318-3065
Marco MasiDepartment of Chemical Science, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0003-0609-8902
Muhammad SulemanBiomedical Research Center (BRC), QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Haritha KalathBiomedical Research Center (BRC), QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0009-0006-5214-9087
Mai M KarousaBiomedical Research Center (BRC), QU Health, Qatar University, Doha P.O. Box 2713, Qatar.
Maha M AyoubBiomedical Research Center (BRC), QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0009-0008-1596-5928
Abdullah A ShaitoBiomedical Research Center (BRC), QU Health, Qatar University, Doha P.O. Box 2713, Qatar.ORCID 0000-0003-3524-7962
Anna AndolfiDepartment of Chemical Science, University of Naples Federico II, 80126 Naples, Italy.ORCID 0000-0001-8949-3654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four sesquiterpenes, namely tomentosin, 11α,13-dihydrotomentosin, inuviscolide, and α-costic acid, were isolated from the aerial parts of the medicinal plant

Indexed as

Antineoplastic Agents, PhytogenicAsteraceaeCell ProliferationSesquiterpenesA549 CellsCell SurvivalCyclooxygenase 2HCT116 CellsHumansLactonesMolecular Docking SimulationPlant ExtractsSTAT3 Transcription FactorAntineoplastic Agents, PhytogenicCyclooxygenase 2LactonesPlant ExtractsPTGS2 protein, humanSesquiterpenesSTAT3 protein, humanSTAT3 Transcription Factortomentosinanticancer activitycovalent molecular dockingDittrichia viscosainuviscolidenetwork pharmacologysesquiterpenestomentosin

Identifiers

PMID42589714
PMCPMC13467573

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.