Evidence map›Paper›PMID 42591157›Full record

ArticleFrontiers in public health2026

Bidirectional longitudinal associations between low anterior resection syndrome and stigma in patients with postoperative LARS: a cross-lagged panel study.

Xiangdong Hu, Qiushi Yin, Mei Cao, Changcui Liang, Hui Yang

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Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xiangdong HuDepartment of General Surgery, Lu'an Hospital of Anhui Medical University (Lu'an People's Hospital), Lu'an, China.
Qiushi YinGraduate College, Wannan Medical University, Wuhu, China.
Mei CaoDepartment of General Surgery, Lu'an Hospital of Anhui Medical University (Lu'an People's Hospital), Lu'an, China.
Changcui LiangDepartment of Urology, Affiliated Hospital of West Anhui Health Vocational College, Lu'an, China.
Hui YangResidency Training and Education Department, Lu'an Hospital of Anhui Medical University (Lu'an People's Hospital), Lu'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the bidirectional longitudinal associations between low anterior resection syndrome (LARS) and stigma among patients with postoperative LARS following sphincter-preserving surgery for rectal cancer. Methods: A total of 201 patients with LARS after sphincter-preserving surgery for rectal cancer were recruited using convenience sampling between March 2024 and June 2025. Follow-up was completed in December 2025. Data were collected at 1 month (T1), 3 months (T2), and 6 months (T3) after discharge using the Low Anterior Resection Syndrome Score (LARS) and the Social Impact Scale (SIS). Of the enrolled participants, 181 with complete data across all follow-up assessments were included in the final cross-lagged panel model analysis. Results: LARS scores decreased from 37.28 ± 1.61 at T1 to 28.64 ± 2.86 at T2 and 27.52 ± 2.38 at T3. Stigma scores declined from 67.47 ± 4.06 at T1 to 60.52 ± 3.96 at T2 and 53.40 ± 4.22 at T3 ( Conclusion: LARS and stigma were longitudinally associated among patients with postoperative LARS following sphincter-preserving surgery for rectal cancer. These findings suggest that both symptom burden and psychosocial adaptation should be considered during postoperative follow-up.

Indexed as

Low Anterior Resection SyndromePostoperative ComplicationsRectal NeoplasmsSocial StigmaAgedFemaleHumansLongitudinal StudiesMaleMiddle Agedcross-lagged panel modellongitudinal studylow anterior resection syndrome (LARS)mental healthrectal cancerstigma

Identifiers

PMID42591157
PMCPMC13461448

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.