ArticleLancet regional health. Americas2026
Pre-existing financial circumstance, job loss, and probable depression among U.S. adults: a prospective population-based cohort study.
Article in Lancet regional health. Americas, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Background: While job loss is associated with adverse mental health, it is unclear if the relationship between job loss and mental health differs across pre-existing financial circumstances (objective financial status or subjective financial strain). Methods: We analyzed data from the nationally representative, longitudinal Cumulative Life Stressors Impact on Mental Health and Well-being study (2023-2024) conducted across the United States. We assessed associations between past-year job loss and probable depression (Patient Health Questionnaire-9, PHQ-9 ≥ 10), balancing on pre-job loss characteristics including objective financial status (USD, household savings ≥$5000) and subjective financial strain (difficulty meeting monthly bills). Propensity score weights were generated using a survey-weighted gradient boosted model. Generalized linear models estimated the odds ratio of probable depression by job loss group, overall and stratified by objective financial status and subjective financial strain. Findings: Among 1023 working-age adults, 79 (8.6%) experienced past-year job loss during the study period. Job loss was associated with higher odds of probable depression among adults with pre-existing subjective financial strain [Conditional Odds Ratio, cOR = 1.62 (95% Confidence Interval (CI): 1.01, 2.59)] but not in the group without subjective financial strain, although the formal test comparing estimates between strain groups was not statistically significant [3.72 (95% CI: 0.39, 35.43)]. Estimates were non-significant across objective financial status groups [<$5000 cOR = 1.56 (95% CI: 0.81, 3.02); ≥$5000 cOR = 1.43 (95% CI: 0.88, 2.32)]. Interpretation: Among working-age adults with pre-existing financial strain, job loss was associated with later probable depression. The presence or absence of $5000 or more in objective savings was not associated with differences in the association between job loss and probable depression. These findings suggest that subjective financial strain prior to job loss may be associated with differential mental health following job loss. Funding: The CLIMB study was supported in part by the de Beaumont Foundation, JHU Nexus Award, InHealth, Hopkins Business of Health Initiative Pilot Award, and Hopkins Center for Health Disparities Solutions Pilot Project Award.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.