Evidence map›Paper›PMID 42593275›Full record

ArticleCPT: pharmacometrics & systems pharmacology2026

Reliable Apparent Permeability Prediction Through Benchmarking, Stability, Uncertainty Quantification, and Explainable Machine Learning.

Rajdeep Mondal, Rajith K R Rajoli, Andrew Owen, Soumitra Samanta

Abstract read
In one paragraph

Article in CPT: pharmacometrics & systems pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajdeep MondalRamakrishna Mission Vivekananda Educational and Research Institute, Belur, India.ORCID https://orcid.org/0009-0004-0854-5045
Rajith K R RajoliCentre of Excellence for Long-Acting Therapeutics, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0002-6015-5712
Andrew OwenCentre of Excellence for Long-Acting Therapeutics, University of Liverpool, Liverpool, UK.
Soumitra SamantaRamakrishna Mission Vivekananda Educational and Research Institute, Belur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apparent permeability (

Indexed as

Machine LearningModels, BiologicalBenchmarkingPermeabilityPharmaceutical PreparationsPrediction AlgorithmsPredictive Learning ModelsQuantitative Structure-Activity RelationshipUncertaintyPharmaceutical Preparationsapparent permeabilityinterpretable QSAR modelingmolecular representation learningmulti‐relational graph neural networksuncertainty quantification

Identifiers

PMID42593275
PMCPMC13471647

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.