Evidence map›Paper›PMID 42593743›Full record

ArticleSleep2026

Nap Timing Matters: Later Siesta Associates with Increased Muscle Mass and Decreased Fat Mass in Spain and the US.

María Rodríguez-Martín, Aishi Ghosh, Richa Saxena, Frank A J L Scheer, Hassan S Dashti, Marta Garaulet

2 registry-linked trialsAbstract read
In one paragraph

Article in Sleep, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02829619 recruitingnot on this map

Meal Timing, Genetics and Weight Loss in a Mediterranean Population

TypeobservationalSponsorUniversidad de MurciaRan2008 to 2032Enrolled5,788ConditionsObesity
NCT02997319 completednot on this map

Shift Work, Heredity, Insulin, and Food Timing (SHIFT) Study

TypeobservationalSponsorMassachusetts General HospitalRan2017 to 2021Enrolled365ConditionsShift Work Type Circadian Rhythm Sleep Disorder, Diabetes Mellitus, Type 2, Circadian Rhythm Sleep Disorder, Shift Work Type, Insulin Resistance
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María Rodríguez-MartínDepartment of Physiology, University of Murcia, Murcia, Spain.ORCID 0000-0002-9877-7728
Aishi GhoshDepartment of Anesthesiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Richa SaxenaDepartment of Anesthesiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2233-1065
Frank A J L ScheerDivision of Sleep Medicine, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2014-7582
Hassan S DashtiDepartment of Anesthesiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1650-679X
Marta GarauletDepartment of Physiology, University of Murcia, Murcia, Spain.ORCID 0000-0002-4066-3509

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
Genetics of chronotype and impact on metabolic diseaseR01DK107859 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Richa Saxena · 2016 to 2026
$4.0M
Food Timing to Mitigate Adverse Consequences of Night WorkR01HL153969 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHEER, FRANK A · 2021 to 2025
$3.9M
Impact of Malatonin, Food Timing and Receptor Variant on Type 2 Diabetes RiskR01DK105072 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI SAXENA, RICHA, SCHEER, FRANK A · 2016 to 2020
$3.2M
Effect of temporal distribution of macronutrient intake on metabolismR01HL164454 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI FRANK A SCHEER · 2023 to 2026
$3.2M
The impact of overnight nutrition support on sleep and circadian rhythm disruption in the ICUR00HL153795 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI DASHTI, HASSAN S. · 2023 to 2025
$747k
NCATS NIH HHS UL1 TR002541NHLBI NIH HHS R00 HL153795NHLBI NIH HHS R01 HL153969NHLBI NIH HHS R01 HL164454NIDDK NIH HHS R01 DK105072NIDDK NIH HHS R01 DK107859
6 · The paper itself

Abstract

STUDY

objectivesPrior studies on siesta and obesity are inconsistent, and the role of siesta timing remains unclear. We examined cross-sectional associations between objectively estimated siesta characteristics and body composition in two populations across two continents.

methodsActigraphy-derived siesta timing (clock time and relative to wake/bedtime), duration, and frequency from 90 adults in the Spanish ONTIME Study (NCT02829619) and 69 adults in the US SHIFT Study (NCT02997319) were analyzed. Outcomes included BMI, waist circumference, body fat percentage, and muscle mass percentage. Associations were assessed using adjusted linear and logistic models.

resultsIn the ONTIME Study (52±10 years, 91% women), each 1-hour later siesta start time was associated with lower BMI (β(SE)=-0.044(0.012) log(kg/m2), p=0.0003), body fat (β(SE)=-0.031(0.011)log(%), p=0.014), waist circumference (β(SE)=-0.026(0.012)log(cm), p=0.009), and higher muscle mass in women (β(SE)=0.019(0.006)log(%), p=0.005). Participants with late siestas (16:12-17:42 h) had ~3.94 kg/m2 lower BMI vs. early siestas (ANCOVA P=0.017). Longer siesta duration was associated with 3.98 higher odds of overweight/obesity (95% CI:1.12-14.18, p=0.033), while higher siesta frequency (days/week) trended toward lower body fat and higher muscle mass (p<0.1). Analyses in the independent SHIFT Study (31±9 years, 62.5% women) were directionally consistent but not statistically significant. Fixed-effect meta-analysis combining both cohorts (n = 159) identified significant associations between later siesta start time and lower BMI, lower body fat percentage, lower waist circumference and higher muscle mass percentage (all p<0.05).

conclusionsLater siesta timing is associated with lower obesity traits and higher muscle mass. Objective multidimensional assessment of siesta may help identify behavioral patterns associated with body composition and inform future intervention studies on weight management.

Indexed as

body composition, actigraphynappingobesitysiesta

Identifiers

PMID42593743
PMCPMC13531324

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.