Evidence map›Paper›PMID 42595897›Full record

ArticleSpinal cord2026

Impact of respiratory muscle training on sleep disordered breathing in people with tetraplegia: a sub-analysis of a randomised controlled trial.

Claire L Boswell-Ruys, R H Chaminda Lewis, Rachel A McBain, Nirupama S Wijesuriya, Danny J Eckert, Bonsan Bonne Lee, Simon C Gandevia, Jane E Butler

Abstract read
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In one paragraph

Article in Spinal cord, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claire L Boswell-Ruys *The Kolling Institute and the School of Medical Scfiences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia. claire.boswell-ruys@sydney.edu.au.ORCID http://orcid.org/0000-0003-4922-5262
R H Chaminda Lewis *University of New South Wales, Sydney, NSW, Australia.
Rachel A McBainRoyal North Shore Hospital, St Leonards, NSW, Australia.
Nirupama S WijesuriyaThe George Institute for Global Health, Newtown, NSW, Australia.
Danny J EckertFHMRI Sleep Health, Flinders University, Adelaide, SA, Australia.ORCID http://orcid.org/0000-0003-3503-2363
Bonsan Bonne LeeUniversity of New South Wales, Sydney, NSW, Australia.
Simon C GandeviaThe Kolling Institute and the School of Medical Scfiences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.
Jane E ButlerThe Kolling Institute and the School of Medical Scfiences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW, Australia.

Funding

Department of Health | National Health and Medical Research Council (NHMRC) 1196261
6 · The paper itself

Abstract

STUDY

designSub-analysis of a randomised controlled trial.

objectivesRespiratory muscle training (RMT) in people with tetraplegia yields marked improvements in inspiratory muscle strength. The present study investigated whether RMT also modifies sleep disordered breathing (SDB) and daytime sleepiness.

settingIndependent research institute in Sydney, Australia.

methodsSixty-two adults with tetraplegia underwent six weeks of supervised RMT. The active-RMT group trained the respiratory muscles through progressive threshold loading to a mean intensity of 50% maximal inspiratory pressure whereas the sham-RMT group experienced the same training protocol, but their device had no progressive threshold load. Primary measures of SDB were obtained using level II ambulatory polysomnograms and daytime sleepiness was assessed using the Epworth Sleepiness Scale (ESS) at baseline and after 6-weeks RMT.

resultsForty-eight participants completed two home-based polysomnograms. Maximal inspiratory pressure (primary outcome) increased more after active intervention than sham, between-group difference 11.8cmH

conclusionsDespite significant increases in inspiratory muscle strength, 6 weeks of supervised respiratory muscle training at a mean intensity of 50% maximal inspiratory pressure does not reduce SDB or daytime sleepiness in people with tetraplegia and severe SDB.

Identifiers

PMID42595897

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.