Evidence map›Paper›PMID 42597532›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2026

Blood pressure control after solid organ transplantation: opportunities for optimizing care.

A M Posthumus, T J Knobbe, D Kremer, M F Eisenga, J S F Sanders, S P Berger, C Smit, F Klont, C T Gan, E A M Verschuuren and 5 more

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Article in Transplant international : official journal of the European Society for Organ Transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

A M PosthumusDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
T J KnobbeDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
D KremerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
M F EisengaDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
J S F SandersDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
S P BergerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
C SmitDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
F KlontDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
C T GanDepartment of Pulmonary Diseases and Tuberculosis, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
E A M VerschuurenDepartment of Pulmonary Diseases and Tuberculosis, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
K DammanDepartment of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
M H de BorstDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
H BlokzijlDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
S J L Bakker *Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
V E de Meijer *Department of Surgery, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension affects 50%-90% of solid organ transplant recipients (SOTR) and is a major driver of cardiovascular disease. Nevertheless, hypertension control has received little attention in this population. We assessed blood pressure control 1 year after heart, liver, lung or kidney transplantation using cross-sectional data from 1112 SOTR (39% female, mean age 57 ± 13 years) from the TransplantLines biobank and cohort study. Suboptimal control was defined as systolic blood pressure >130 mmHg or diastolic blood pressure >80 mmHg. Overall, 997 (90%) SOTR had hypertension. Suboptimal control occurred in 721 (72%), including 146 (20%) who received no antihypertensive treatment despite elevated blood pressure. Rates of suboptimal control were consistently high across organ types (71%-84%). Older age (OR = 1.03; 95%CI1.01-1.04), diabetes (OR = 1.99; 95%CI1.18-3.36), and higher cholesterol (OR = 1.23; 95%CI1.01-1.51) were independently associated with suboptimal control. Among treated SOTR, recipients were older (OR = 1.03; 95%CI1.01-1.05), more often male (OR = 1.55; 95%CI1.03-2.34), and had more prior cardiovascular events (OR = 2.06; 95%CI1.14-3.95). In sensitivity analyses using alternative blood pressure thresholds, suboptimal control remained common, affecting 40% of hypertensive SOTR using a ≤140/90 mmHg threshold. In conclusion, nearly three out of four hypertensive SOTR have suboptimal blood pressure control at 1 year after transplantation with a ≤130/80 mmHg threshold, highlighting a substantial care gap in post-transplant management.

Indexed as

Antihypertensive AgentsBlood PressureHypertensionOrgan TransplantationAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk FactorsAntihypertensive Agentsblood pressure managementhypertensionsolid organ transplantationsuboptimal treatmentuncontrolled hypertension

Identifiers

PMID42597532
PMCPMC13468530

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.