Evidence map›Paper›PMID 42598174›Full record

ArticleRegenerative biomaterials2026

Epoxomicin-functionalized thermosensitive hydrogel rescues bone defects in osteoporosis by the NF-κB signaling pathway.

Liqun Jiang, Qijia Sui, Chen Sun, Chen Li, Shuai Wang, Zijiao Zhang, Huiying Liu, Guowu Ma

Abstract read
In one paragraph

Article in Regenerative biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Liqun JiangSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Qijia SuiSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Chen SunSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Chen LiSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Shuai WangSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Zijiao ZhangSchool of Stomatology, Dalian Medical University, Dalian 116044, China.
Huiying LiuSchool of Stomatology, Dalian Medical University, Dalian 116044, China.ORCID https://orcid.org/0000-0002-0385-3557
Guowu MaSchool of Stomatology, Dalian Medical University, Dalian 116044, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the clinical challenge of difficult bone defect healing in osteoporosis patients, this study developed a functional delivery system based on a thermosensitive hydrogel loaded with epoxomicin (CS-βGP@10Epoxomicin). This system possesses injectability and body-temperature-triggered

Indexed as

epoxomicininflammationosteoclast differentiationosteoporosissmart hydrogel

Identifiers

PMID42598174
PMCPMC13471993

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.