Evidence map›Paper›PMID 42598534›Full record

ReviewSaudi medical journal2026

The Case for Gulf Region-Specific Peripheral Artery Disease Trials:

Hosaam H Nasr, Faisal A Almudaiheem

Abstract readReview
In one paragraph

Review in Saudi medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hosaam H NasrConsultant, Division of Vascular Surgery, Department of Surgery, King Abdulaziz Medical city, National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia.
Faisal A AlmudaiheemFellow Vascular Surgery, Division of Vascular Surgery, Department of Surgery, King Abdulaziz Medical city, National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia.ORCID 0009-0000-1610-4267

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral artery disease (PAD) research is globally underrepresented, with landmark trials like Best Endovascular Surgical Therapy for Patients with Critical Limb Ischemia and Bypass versus Angioplasty in Severe Ischemia of the Leg predominantly featuring white, Western populations. These studies fail to account for the unique clinical landscape of the Gulf region, where PAD prevalence reaches up to 13.7%. Gulf patients present at younger ages and face a disproportionately high diabetes burden, with regional prevalence near 18%, nearly double that of Europe. Beyond metabolic factors, the Gulf population exhibits distinct genetic architectures, including high rates of consanguinity and familial hypercholesterolemia. Because Western-derived data cannot be universally applied, there is an urgent imperative for region-specific PAD trials that incorporate local epidemiology, culturally adapted outcome measures, and localized risk assessment models.

Indexed as

Clinical Trials as TopicPeripheral Arterial DiseaseHumansMiddle EastPrevalenceChronic limb threatening ischemiaClinical diversityCLTIDiabetes mellitusPADPeripheral arterial disease

Identifiers

PMID42598534
PMCPMC13471448

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.