Evidence map›Paper›PMID 42598560›Full record

ArticleMaterials today. Bio2026

3D-printed multifunctional composite scaffolds incorporating copper ions/amoxicillin/hydroxyapatite for synergistic antibacterial and vascularized bone regeneration.

Yongteng Song, Haiguang Zhang, Yuxuan Tang, Jie Wang, Shujun Zhang, Xinchao Gao, Yuanhang Yang, Qingxi Hu, Changjin Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yongteng SongRapid Manufacturing Engineering Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, 200444, China.
Haiguang ZhangRapid Manufacturing Engineering Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, 200444, China.
Yuxuan TangSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.
Jie WangSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.
Shujun ZhangSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.
Xinchao GaoSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.
Yuanhang YangSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.
Qingxi HuRapid Manufacturing Engineering Center, School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, 200444, China.
Changjin HuangSchool of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore, 639798, Republic of Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The repair of large bone defects presents significant clinical challenges due to the complex healing process involving early infection control, followed by angiogenesis and osteogenesis. However, conventional biological scaffolds often fail to support these sequential stages, limiting their effectiveness in achieving complete and functional bone regeneration. To address this challenge, a multifunctional vascularized composite bone scaffold was fabricated in this study using 3D printing technology, utilizing gelatin (GEL) and sodium alginate (SA) as the hydrogel matrix, with incorporation of copper ions (Cu

Indexed as

3D printingAngiogenesisAntibacterialLarge bone defect repairMultifunctional composite bone scaffoldOsteogenesis

Identifiers

PMID42598560
PMCPMC13471327

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.