Evidence map›Paper›PMID 42599336›Full record

ArticleMycopathologia2026

First Reported Neonatal Invasive Candidozyma auris (Candida auris) Infection in Brazil: Successful Management, Evolving Amphotericin B Resistance, and Infection Containment.

Angelica Zaninelli Schreiber, Ana Luisa Perini Leme Giordano, Barbara Cipulo Legabão, Lais Pontes, Edson Aparecido da Luz, Giuliana D'Angelo Moreno, Gisele Giuliane Guedes, Stefânia Lucizani Pacífico, Mariana Marques Fernandes Moreira de Souza, Tânia Sueli de Andrade and 2 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Mycopathologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Angelica Zaninelli SchreiberPathology Department, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil. zaninele@unicamp.br.
Ana Luisa Perini Leme GiordanoPathology Department, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Barbara Cipulo LegabãoPathology Department, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Lais PontesPathology Department, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Edson Aparecido da LuzMicrobiology Laboratory, Clinical Pathology Division, Clinical Hospital, UNICAMP, Campinas, São Paulo, Brazil.
Giuliana D'Angelo MorenoWomen's Hospital, UNICAMP, Campinas, São Paulo, Brazil.
Gisele Giuliane GuedesWomen's Hospital, UNICAMP, Campinas, São Paulo, Brazil.
Stefânia Lucizani PacíficoWomen's Hospital, UNICAMP, Campinas, São Paulo, Brazil.
Mariana Marques Fernandes Moreira de SouzaWomen's Hospital, UNICAMP, Campinas, São Paulo, Brazil.
Tânia Sueli de AndradeDepartment of Culture Collection, Adolfo Lutz Institute, Secretary of Health, São Paulo, SP, Brazil.
Carolina Carvalho Ribeiro do ValleWomen's Hospital, UNICAMP, Campinas, São Paulo, Brazil.
Jamil Pedro de Siqueira CaldasDepartment of Pediatrics, School of Medical Sciences, UNICAMP, Campinas, São Paulo, Brazil. jpcaldas@unicamp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the first neonatal invasive Candida auris infection in Brazil and its successful clinical and infection control management.

methodsRetrospective description of the clinical course, microbiological findings, antifungal susceptibility evolution, and follow-up of an extremely preterm infant.

resultsA 25 + 4-week male neonate developed bloodstream and urinary C. auris infection during the first week of life. Progressive amphotericin B resistance in urine isolates required the addition of fluconazole. No secondary NICU cases occurred.

conclusionEarly diagnosis, serial susceptibility testing, and immediate containment measures enabled successful treatment and prevented nosocomial spread.

Indexed as

Amphotericin BAntifungal AgentsCandida aurisCandidiasis, InvasiveDrug Resistance, FungalBrazilFluconazoleHumansInfant, NewbornInfection ControlMaleMicrobial Sensitivity TestsRetrospective StudiesAmphotericin BAntifungal AgentsFluconazoleCandida aurisInfantInfection controlInvasive fungal infectionsPrematureSentinel surveillance

Identifiers

PMID42599336

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.