ArticleJapanese journal of radiology2026
Comparison of lesion detection rates between FAPI PET/CT and
Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
4 authors.
Funding
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Abstract
objectivesTo compare the lesion detection rates of fibroblast activation protein inhibitor (FAPI) PET/CT and
methodsDatabases including PubMed, Embase, Cochrane Library, Scopus, and Web of Science were searched for head-to-head studies comparing FAPI and FDG for HCC lesion detection up to March 2026. Two researchers independently performed literature screening and data extraction, and assessed the risk of bias using the QUADAS-2 tool. Meta-analysis was conducted using R 4.5.3 software. The primary outcome was lesion detection-rate difference, expressed as risk difference (RD) with 95% confidence intervals (CIs). Random-effects models were used for pooled analyses. Subgroup analyses were performed according to lesion size and treatment status when data were available. Anatomical-site findings were summarized descriptively because pooled analysis was not considered appropriate.
resultsEight reports were included in the qualitative synthesis, and 5 studies/outcomes providing HCC-specific paired comparative data were included in the main quantitative synthesis. Overall, FAPI PET/CT showed a significantly higher lesion detection rate than
conclusionIn the available HCC-specific head-to-head studies, FAPI PET/CT was associated with a higher lesion detection rate than
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.