Evidence map›Paper›PMID 42602973›Full record

ArticleComputational psychiatry (Cambridge, Mass.)2026

OCD Compulsions as Aberrant Integration of Uncertainty from Local Goals to Global Goals.

Andra Geana, Christina L Boisseau, Steven Rasmussen, Michael J Frank

Abstract read
In one paragraph

Article in Computational psychiatry (Cambridge, Mass.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andra GeanaProvidence College, Providence, RI, US.ORCID https://orcid.org/0000-0001-5496-150X
Christina L BoisseauNorthwestern Feinberg School of Medicine, Northwestern, Chicago, IL, US.ORCID https://orcid.org/0000-0003-0925-1917
Steven RasmussenBrown University Alpert Medical School, Providence, RI, US.
Michael J FrankBrown University Carney Institute for Brain Science, Providence, RI, US.ORCID https://orcid.org/0000-0001-8451-0523

Funding

The neural network of OCD, linking NHP and human studiesP50MH106435 · NIMH · UNIVERSITY OF ROCHESTER · PI Suzanne N Haber · 2015 to 2026
$28.9M
Brown Postdoctoral Training Program in Computational PsychiatryT32MH126388 · NIMH · BROWN UNIVERSITY · PI MICHAEL J. FRANK, STEPHANIE Ruggiano JONES · 2021 to 2026
$2.1M
NIMH NIH HHS P50 MH106435NIMH NIH HHS T32 MH126388
6 · The paper itself

Abstract

Recent years have seen unprecedented increases in compulsive behaviors, even in previously undiagnosed populations. Yet, despite their rising prevalence and the fact that compulsions-notably associated with obsessive-compulsive disorder (OCD), but also a key feature of other disorders such a hoarding or body dysmorphic disorder-significantly hamper daily function, the specific mechanisms of their formation remain unknown. Previous research holds mixed findings on compulsivity-linked cognitive deficits, and, while many accounts assume that compulsions aim to reduce anxiety, most individuals with anxiety do not develop compulsions-suggesting that the anxiety-reduction account is incomplete. We propose here a broader, uncertainty-resolving account of compulsivity, that bypasses the commonly-used, single-goal structure of many cognitive tasks to leverage the real-world hierarchical structure of goals-with "

Indexed as

compulsivitycomputational modellinglearningobsessive-compulsive disorderOCDreinforcement learning

Identifiers

PMID42602973
PMCPMC13475530

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.