ArticlePhysical and engineering sciences in medicine2026
A hybrid Wavelet-EfficientNetV2-Vision transformer framework for multiclass brain tumor MRI classification.
Article in Physical and engineering sciences in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Accurate classification of brain tumors from MRI scans requires models capable of capturing both fine-grained structural details and broader contextual patterns. This study proposes a hybrid Wavelet-EfficientNetV2-Vision Transformer (ViT) framework that integrates multi-resolution frequency enhancement, hierarchical spatial encoding, and global dependency modeling into a unified representation. The Discrete Wavelet Transform (DWT) enriches directional and boundary-aware features, EfficientNetV2 extracts robust localized patterns, and the ViT captures long-range contextual relationships essential for differentiating tumor categories with overlapping visual characteristics. The method was evaluated on the Kaggle-MRI dataset consisting of four classes: glioma, meningioma, pituitary tumor, and no tumor. Experimental results show that the proposed model achieves 98.25% accuracy, with consistent gains in precision, recall, and F1-score compared to standalone CNNs, transformer models, and recent state-of-the-art approaches. Additional analyses, including confusion matrices, ROC-AUC evaluation, and stratified five-fold cross-validation, demonstrate strong class-level stability and generalization. These findings indicate that combining frequency, spatial, and contextual information provides a more discriminative feature space for MRI-based tumor classification. The proposed framework offers a promising direction for developing reliable and high-performance computer-aided diagnosis systems, with future work aimed at multi-center validation and extension to volumetric (3D) modeling.
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