ArticleAmerican journal of physiology. Cell physiology2026
Insulin-regulated actin dynamics is disrupted in a human keratinocyte model of Hailey-Hailey disease.
Ruby Gupta, Akash Chinchole, Ngozi P Paul, Mrinal K Sarkar, Johann E Gudjonsson, Ajay Verma, Rajini Rao
Abstract read
In one paragraphArticle in American journal of physiology. Cell physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
7 authors.
Ruby GuptaDepartment of Physiology, Pharmacology & Therapeutics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0001-8101-5930 Akash ChincholeDepartment of Physiology, Pharmacology & Therapeutics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0003-0371-8811 Ngozi P PaulDepartment of Physiology, Pharmacology & Therapeutics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Mrinal K SarkarDepartment of Dermatology, Taubman Medical Research Institute, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0001-8505-4259 Johann E GudjonssonDepartment of Dermatology, Taubman Medical Research Institute, University of Michigan, Ann Arbor, Michigan, United States.
Ajay VermaFormation Venture Engineering Foundry, Topsfield, Massachusetts, United States.
Rajini RaoDepartment of Physiology, Pharmacology & Therapeutics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.ORCID 0000-0002-1833-5971 Funding
University of Michigan Skin Biology and Diseases Resource-based CenterP30AR075043 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Johann Eli Gudjonsson · 2019 to 2026
$6.6MTowards a targeted therapy for Hailey Hailey DiseaseR03TR005427 · NCATS · JOHNS HOPKINS UNIVERSITY · PI RAO, RAJINI · 2024 to 2024
$164kFormation Venture Engineering Foundry N/AHHS | NIH | National Center for Advancing Translational Sciences (NCATS) 1R03TR005427HHS | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 1P30AR075043NCATS NIH HHS R03 TR005427NIAMS NIH HHS P30 AR075043
6 · The paper itselfAbstract
Indexed as
Actin CytoskeletonActinsCalcium-Transporting ATPasesInsulinKeratinocytesPemphigus, Benign FamilialCell LineCell MovementHumansSignal TransductionWound HealingActinsATP2C1 protein, humanCalcium-Transporting ATPasesInsulinactin cytoskeletoncalcium ATPaseGolgiinsulin signalingskin
Identifiers
PMID42605981
PMCPMC13583997
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