ReviewResearch (Washington, D.C.)2026
The Scalp Microbiome-Hair Axis: Mechanisms and Therapeutic Translation.
Review in Research (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hair loss is common and can markedly impair quality of life, yet the contribution of the scalp microbiome to alopecia remains fragmented across disease subtypes and mechanistic levels. This review aims to construct a clinically relevant and mechanistically coherent framework for the scalp microbiome-hair axis. We first summarize the composition and physiological functions of the scalp microbiome, including its roles in barrier integrity, immune regulation, and nutrient metabolism. We then compare dysbiosis patterns across androgenetic alopecia, alopecia areata, seborrheic dermatitis-associated hair loss, and folliculitis/scarring alopecia. This comparison identifies a shared pathogenic layer-barrier disruption, innate immune activation, altered lipid or metabolite processing, and impaired anagen support-together with subtype-selective mechanisms, including immune-privilege collapse in alopecia areata, androgen-lipid-microbiome coupling in androgenetic alopecia,
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.