Evidence map›Paper›PMID 42609713›Full record

ArticleHemaSphere2026

An Italian cartography of VEXAS-related thrombosis.

Giorgia Ranucci, Maria Rosaria Pascale, Vittorio Forte, Elisa Diral, Corrado Campochiaro, Jacqueline Ferrari, Mariachiara Cuccaro, Chiara Cattaneo, Francesca Crisafulli, Lucia Cardillo and 33 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HemaSphere, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

43 authors.

Giorgia RanucciDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.ORCID https://orcid.org/0009-0009-3431-7333
Maria Rosaria PascaleDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Vittorio ForteClinical Biochemistry Department of Laboratory Medicine University of Rome Tor Vergata Rome Italy.
Elisa DiralUnit of Hematology and Bone Marrow Transplantation IRCCS San Raffaele Hospital Milan Italy.ORCID https://orcid.org/0000-0002-4994-7719
Corrado CampochiaroUnit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR) IRCCS Ospedale San Raffaele & Vita-Salute San Raffaele University Milan Italy.
Jacqueline FerrariUnit of Molecular Hematology & Precision Medicine Fondazione IRCCS Policlinico San Matteo Pavia Italy.
Mariachiara CuccaroHematology Unit Azienda Ospedaliero Universitaria Senese, University of Siena Siena Italy.
Chiara CattaneoRheumatology and Clinical Immunology Unit, ASST Spedali Civili and Department of Clinical and Experimental Sciences University of Brescia Brescia Italy.
Francesca CrisafulliRheumatology and Clinical Immunology Unit, ASST Spedali Civili and Department of Clinical and Experimental Sciences University of Brescia Brescia Italy.
Lucia CardilloDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Valeria RenolaDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Elisa MeddiDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Marianna VelocciDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Elisa CascianiDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Francesca RomanoDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Pellegrino MustoDepartment of Precision and Regenerative Medicine and Ionian Area "Aldo Moro" University Bari Italy.
Serafina BarbatoHematology, Department of Clinical Medicine and Surgery University of Naples "Federico II" Naples Italy.
Giorgia BattipagliaHematology, Department of Clinical Medicine and Surgery University of Naples "Federico II" Naples Italy.ORCID https://orcid.org/0000-0002-0695-3879
Marco FrigeniHematology and Bone Marrow Transplant Unit ASST Papa Giovanni XXIII Bergamo Italy.
Erika MorsiaHematology Department Azienda Ospedaliera Universitaria Ospedali Riuniti di Ancona Ancona Italy.
Arianna SaviDepartment of Clinical and Biological Sciences University of Turin Turin Italy.
Cristina PapayannidisIRCCS Azienda Ospedaliero-Universitaria di Bologna Istituto di Ematologia "Seràgnoli" Bologna Italy.
Elena CrisàDivision of Hematology, Department of Translation Medicine Università del Piemonte Orientale and Azienda Ospedaliero-Universitaria Maggiore della Carità Novara Italy.
Laura CicconiDepartment of Hematology Polo Universitario Pontino, S.M. Goretti Hospital Latina Italy.
Isabella CapodannoSOC Ematologia Azienda USL-IRCSS di Reggio Emilia Reggio Emilia Italy.
Alfonso FiumarellaUOC Onco-Ematologia Plesso Ospedaliero "Andrea Tortora" di Pagani Salerno Italy.
Antonio PieriniSection of Hematology, Department of Medicine and Surgery, Center for Hemato-Oncological Research (CREO) University of Perugia Perugia Italy.
Massimo BrecciaDepartment of Translational and Precision Medicine Sapienza University of Rome Rome Italy.
Giovanni OrsoliniUnità Operativa di Reumatologia Azienda Ospedaliera Universitaria Integrata di Verona Verona Italy.
Giulia RivoliUO Ematologia e Terapie Cellulari IRCCS Ospedale Policlinico San Martino Genova Italy.
Sara BindoliRheumatology Unit, Department of Medicine University of Padova Padua Italy.
Davide FirinuDepartment of Medical Sciences and Public Health University of Cagliari Cagliari Italy.
Antonio VitaleRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences University of Siena and Azienda Ospedaliero-Universitaria Senese Siena Italy.
Bruno FattizzoDepartment of Oncology and Hemato-Oncology University of Milan Milan Italy.ORCID https://orcid.org/0000-0003-0857-8379
Monica BocchiaHematology Unit Azienda Ospedaliero Universitaria Senese, University of Siena Siena Italy.
Luca CantariniRheumatology Unit, Department of Medical Sciences, Surgery and Neurosciences University of Siena and Azienda Ospedaliero-Universitaria Senese Siena Italy.
Chiara PintonDepartment of Biomedical Sciences Humanitas University Milan Italy.
Gabriele TodiscoDepartment of Biomedical Sciences Humanitas University Milan Italy.
Nicola ToschiDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Paola TriggianeseDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Adriano VendittiDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.ORCID https://orcid.org/0000-0002-0245-0553
Maria Teresa VosoDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.
Carmelo GurnariDepartment of Biomedicine and Prevention University of Rome Tor Vergata Rome Italy.ORCID https://orcid.org/0000-0001-6829-5544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombotic events (TEs) occur in up to 40% of patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, and somatic (VEXAS) syndrome, but data on its clinical-genomics features and anticoagulation strategies are limited. To gain more insight into this, we conducted a two-step study evaluating the prevalence and outcome of TE in VEXAS. First, among 1086 patients followed for TEs, 198 were men aged >40 years with unprovoked thrombosis and no known thrombophilia; 21 also had at least one VEXAS-compatible feature and underwent

Identifiers

PMID42609713
PMCPMC13479803

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.