Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Dalton J HueyDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0001-7316-790X
Eduardo GuadarramaDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Jean-Marc DeKeyserDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0001-9863-6274
Carlos G VanoyeDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0002-4935-1122
Christine Q SimmonsDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Qianru LiDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Emily K StroupDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Zhe JiDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.ORCID 0000-0002-1809-8099
Alfred L GeorgeDepartment of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.
Funding
Chemistry of Life Processes Predoctoral Training ProgramT32GM105538 · NIGMS · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2013 to 2022
$2.7M
Characterizing functional translation in putative 'noncoding' regions of a genome: Admin SupplR35GM138192 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JI, ZHE · 2020 to 2024
$2.1M
An ultra-low-input RNase footprinting assay to quantify cytosolic and mitochondrial translation simultaneouslyR01HL161389 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JI, ZHE · 2022 to 2025
$1.9M
Pathophysiology of KCNQ2-related DisordersR01NS137587 · NINDS · NORTHWESTERN UNIVERSITY · PI Alfred L. George, Evangelos Kiskinis · 2025 to 2026
$1.7M
SyncroPatch 384 Automated Patch Clamp InstrumentS10OD034362 · OD · NORTHWESTERN UNIVERSITY · PI GEORGE, ALFRED L. · 2023 to 2023
$599k
Exploiting KCNQ2 upstream open reading frames for therapeutic opportunityF31NS135753 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Dalton Jun-Da Huey · 2024 to 2026
Upstream open reading frames (uORFs) within the 5'-untranslated region (5'-UTR) of messenger RNA transcripts can regulate protein translation. Despite widespread prevalence within the human genome, they remain unidentified for many clinically relevant genes. A gene frequently associated with neonatal-onset epilepsy is
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.
An upstream open reading frame represses translation of the neuronal potassium channel KCNQ2. · full record | Socratic