Effect of Epigallocatechin Gallate Supplementation on Inflammation, Iron Status, and Metabolomic Profiles in Women With Obesity: A Pilot Randomized Controlled Trial.

Sixtus Aguree, Kedir N Turi, Alexandra R Handt, Marian Kohut, Manju B Reddy

Abstract readRandomized Controlled Trial

In one paragraph

Trial report in Molecular nutrition & food research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sixtus AgureeDepartment of Applied Health Science, Indiana University School of Public Health, Bloomington, Indiana, USA.

Kedir N TuriDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health, Bloomington, Indiana, USA.

Alexandra R HandtDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.

Marian KohutDepartment of Kinesiology, Iowa State University, Ames, Iowa, USA.

Manju B ReddyDepartment of Food Science and Human Nutrition, Iowa State University, Ames, Iowa, USA.

Funding

Doris A. Adams endowment chair funds from the Department of Food Science and Human Nutrition in the College of Human Sciences at Iowa State University

6 · The paper itself

Abstract

Obesity in women of reproductive age is often associated with low-grade inflammation and functional iron deficiency. Epigallocatechin gallate (EGCG), a major green tea catechin, has antioxidant, anti-inflammatory, and metabolic-regulating properties but may also interfere with iron absorption. This randomized, double-blind, placebo-controlled pilot study evaluated the effects of EGCG on lipid profile, inflammation, iron status, and plasma metabolomics in women with obesity. Seventeen participants (BMI ≥30 kg/m

Indexed as

CatechinInflammationIronObesityAdultBiomarkersDietary SupplementsDouble-Blind MethodFemaleHepcidinsHumansMetabolomicsPilot ProjectsYoung AdultBiomarkersCatechinepigallocatechin gallateHepcidinsIronepigallocatechin gallateinflammationiron homeostasislipid metabolismmetabolomicsobesity

Identifiers

PMID42613905

DOI10.1002/mnfr.70575

PMCPMC13487353

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.