Evidence map›Paper›PMID 42614183›Full record

Trial reportFrontiers in nutrition2026

Laboratory-selected, probiotic

Erina Ushizawa, Takehiko Yasueda, Ayatake Nakano, Tomohiro Sugino, Masahiro Fukuda, Hiroshi M Ueno

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erina UshizawaMilk Science Research Institute, Megmilk Snow Brand Co., Ltd., Kawagoe, Japan.
Takehiko YasuedaMilk Science Research Institute, Megmilk Snow Brand Co., Ltd., Kawagoe, Japan.
Ayatake NakanoMilk Science Research Institute, Megmilk Snow Brand Co., Ltd., Kawagoe, Japan.
Tomohiro SuginoSoiken Inc., Toyonaka, Japan.
Masahiro FukudaFukuda Clinic, Osaka, Japan.
Hiroshi M UenoMilk Science Research Institute, Megmilk Snow Brand Co., Ltd., Kawagoe, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Although the gut microbiome is involved in the pathogenesis of knee osteoarthritis (OA), the effects of dietary supplementation remain controversial. Probiotics are a promising option for lifestyle management of inflammatory diseases. This study aimed to investigate the effects of dietary supplementation with probiotics on subjective symptoms and the gut microbiome in adults with knee pre-OA. Methods: For the Results: Discussion: LS2687 supplementation was well-tolerated and provided new insights into the probiotic management of knee pre-OA. The gut-knee axis should be considered in the management of symptoms with knee pre-OA. Clinical Trial Registration: https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000059864, identifier [R000059864].

Indexed as

gut microbiomeknee osteoarthritisLigilactobacillus salivariuspre-osteoarthritisprobioticsrandomized controlled trial

Identifiers

PMID42614183
PMCPMC13481194

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.