ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2026
Following the curvature: Sulcal versus gyral cortical localization of cerebral microbleeds in cerebral amyloid angiopathy.
Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebrospinal fluid (CSF) mediated brain clearance and inflammation are known features of cerebral amyloid angiopathy (CAA), that may be affected by the cortical gyrencephalic structure. Considering these processes in the development of cerebral microbleeds (CMB), we compared sulcal and gyral cortical CMB densities in sporadic and Dutch-type hereditary CAA (sCAA and D-CAA). CMBs were annotated on 3-Tesla susceptibility weighted imaging. Sulcal and gyral cortex-maps were created using FreeSurfer's curvature analysis. Sulcal and gyral CMB densities were compared using a generalized linear mixed model. Sensitivity analyses examined sulcal versus gyral CMB densities (1) after adjusting for disease type (sCAA vs D-CAA) and (2) in participants with lobar and deep CMBs. Thirty-nine participants were included (28/11 sCAA/D-CAA, mean age 70/53 years). Sulcal CMB density was higher than gyral CMB density (
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.