Evidence map›Paper›PMID 42620034›Full record

ArticleResearch square2026

Metastatic Cancers Exploit Vagal Sensory Neurons and Neural Repair Programs to Colonize New Tissues.

Tiago H Zaninelli, Telma Saraiva-Santos, Gustavo Gastã Davanzo, Alliny Cs Bastos, Ruben Silva, Jose C de Lima-Junior, Amanda Martins Dionisio, Soraia Mendes-Pierotti, Kennedy K Reed, Yuriy Kirichok and 7 more

Abstract readPreprint
In one paragraph

Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tiago H ZaninelliDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
Telma Saraiva-SantosDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
Gustavo Gastã DavanzoBrain Immunology and Glia (BIG) Center, Washington University in St. Louis, Saint Louis, MO, USA.ORCID 0000-0002-6723-1933
Alliny Cs BastosDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
Ruben SilvaBrain Immunology and Glia (BIG) Center, Washington University in St. Louis, Saint Louis, MO, USA.ORCID 0009-0000-5074-2537
Jose C de Lima-JuniorDepartment of Biochemistry & Molecular Biophysics, Washington University in St. Louis, St. Louis, MO, USA.
Amanda Martins DionisioDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
Soraia Mendes-PierottiDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
Kennedy K ReedDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
Yuriy KirichokDepartment of Biochemistry & Molecular Biophysics, Washington University in St. Louis, St. Louis, MO, USA.ORCID 0000-0001-7155-843X
Rubia CasagrandeDepartment of Pharmaceutical Sciences, Center of Health Sciences, Londrina State University, Londrina, Paran·, Brazil.
Waldiceu A VerriDepartment of Immunology, Parasitology, and Pathology, Center of Biological Sciences, Londrina State University, Londrina, Paran·, Brazil.
Igor SmirnovBrain Immunology and Glia (BIG) Center, Washington University in St. Louis, Saint Louis, MO, USA.
Jason WeberDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.ORCID 0000-0002-1069-6983
David Y ChenDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.ORCID 0000-0002-3681-6576
Jonathan KipnisBrain Immunology and Glia (BIG) Center, Washington University in St. Louis, Saint Louis, MO, USA.ORCID 0000-0002-3714-517X
Felipe A Pinho-RibeiroDepartment of Medicine, School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.ORCID 0000-0003-4264-9839

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI Shawn Shafer · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI David W Piston · 2013 to 2026
$27.1M
IVIS Spectrum CT Preclinical In Vivo Imaging SystemS10OD027042 · OD · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2019 to 2019
$599k
Multispectral Optoacoustic Tomography (MSOT) SystemS10OD025264 · OD · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2018 to 2018
$544k
NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NIDDK NIH HHS P30 DK020579NIH HHS S10 OD025264NIH HHS S10 OD027042
6 · The paper itself

Abstract

Metastasis remains the leading cause of cancer-related mortality, yet the mechanisms that enable disseminated tumor cells to colonize distant organs remain incompletely understood.

Identifiers

PMID42620034
PMCPMC13484412

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.