Evidence map›Paper›PMID 42620065›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Biobehavioral pain profiling of minoritized adults with chronic widespread pain and clinical obesity before and after bariatric surgery: study protocol for a longitudinal, observational cohort study.

Ericka N Merriwether, Mariam Maqsood, Sally M Vanegas, Steven Em, Natalia Perez, Manish Parikh, Blanca Ruiz-Guerenabarrena, Claudia Humala-Martinez, Briana Lopez, Roger B Fillingim and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ericka N MerriwetherDepartment of Physical Therapy, NYU Steinhardt School of Education, Culture, and Human Development, New York University, New York, NY, USA.ORCID 0000-0002-2507-6058
Mariam MaqsoodDepartment of Physical Therapy, NYU Steinhardt School of Education, Culture, and Human Development, New York University, New York, NY, USA.
Sally M VanegasDepartment of Medicine, NYU Grossman School of Medicine, New York University, New York, NY, USA.
Steven EmNew York City Health and Hospitals/Bellevue Hospital Center, New York, NY, USA.
Natalia PerezDepartment of Physical Therapy, NYU Steinhardt School of Education, Culture, and Human Development, New York University, New York, NY, USA.
Manish ParikhNew York City Health and Hospitals/Bellevue Hospital Center, New York, NY, USA.ORCID 0000-0002-8612-5407
Blanca Ruiz-GuerenabarrenaDepartment of Physical Therapy, NYU Steinhardt School of Education, Culture, and Human Development, New York University, New York, NY, USA.
Claudia Humala-MartinezDepartment of Physical Therapy, NYU Steinhardt School of Education, Culture, and Human Development, New York University, New York, NY, USA.
Briana LopezDepartment of Physical Therapy, NYU Steinhardt School of Education, Culture, and Human Development, New York University, New York, NY, USA.ORCID 0009-0005-9797-9546
Roger B FillingimPain Research and Innovation Center of Excellence, University of Florida, Gainesville, FL, USA.
Melanie JayDepartment of Medicine, NYU Grossman School of Medicine, New York University, New York, NY, USA.ORCID 0000-0001-7343-3120

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic widespread pain (CWP) is highly prevalent among minoritized adults with clinical obesity, and symptom management is challenging. Weight loss via bariatric surgery is often recommended to improve musculoskeletal pain. However, there is significant variation in pain trajectories following bariatric surgery, and the impact of weight loss on movement-evoked pain is largely unknown. The current study aims to systematically characterize and quantify longitudinal changes in pain at rest and movement-evoked pain up to 6 months post-surgery, and to determine whether pain modulatory mechanisms, joint motion, and mechanical loading biosignatures mediate the relationship between weight loss and pain change. This study protocol details the research methodologies and procedures for a prospective observational cohort study of 60 individuals undergoing bariatric surgery for weight loss. Participants will complete questionnaires, anthropometric measurements, clinical and experimental pain testing, functional testing, and a standardized movement testing battery to assess joint motion and mechanical loading using camera-based motion capture before and at 3 and 6 months post-bariatric surgery. Generalized linear mixed models to assess the significance of changes in PAR, MEP, and all patient-reported outcome measures. Reduced models will treat the main effect of time as a fixed factor, and intra-individual repeated measures as random effects. Ethics and dissemination: This study protocol has been registered as an observational study with ClinicalTrials.gov (NCT0675386), version #1, in the United States and has been approved by the NYU Langone Health Institutional Review Board (IRB#: i21-01652) and the New York City Health + Hospitals/Bellevue Research Office (Bellevue Study ID #: STUDY00003739). Study results will be published in peer-reviewed journals and presented at national and international conferences and community events.

Indexed as

bariatric surgerychronic painfunctionmovementobesitypain disparitiesweight losswidespread pain

Identifiers

PMID42620065
PMCPMC13484781

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.