ReviewFrontiers in nutrition2026
Personalized nutrition for healthy aging: precision diets based on genomic, metabolic, and microbiome profiles.
Review in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
7 authors.
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Abstract
The global increase in life expectancy has been accompanied by a parallel rise in the burden of chronic diseases, many of which are influenced by diet and lifestyle. Conventional dietary guidelines, though broadly beneficial, often fail to account for the wide heterogeneity in nutritional needs, metabolic responses, and health trajectories observed among older adults. This limitation has spurred interest in personalized nutrition-a precision approach that leverages individual genomic, metabolomic, and gut microbiome profiles to tailor dietary interventions for healthy aging. Recent advances in omics technologies have deepened our understanding of how genes, circulating metabolites, and microbial ecosystems interact with diet to influence disease risk, physical function, and longevity. This review explores the conceptual foundations, technological enablers, and clinical applications of personalized nutrition, highlighting key evidence from 2020 to 2025. It examines how precision models are being used to improve outcomes in older adults, discusses ethical and social barriers to implementation, and outlines future directions including artificial intelligence and real-time monitoring tools. Personalized nutrition represents a transformative opportunity to shift from population-based dietary advice to individualized strategies that can promote resilience, reduce frailty, and extend healthspan in the aging global population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.