Evidence map›Paper›PMID 42620933›Full record

ArticleJournal of extracellular biology2026

Extracellular Vesicle-Based miRNA Profiling in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Secondary Analysis of the MULTISITE Clinical Trial.

Katja Lund Cliff, Dominic Guanzon, Andrew Lai, Katherin Scholz-Romero, Gunna Christiansen, Aase Handberg, Carlos Salomon, Maiken Mellergaard

Abstract read
In one paragraph

Article in Journal of extracellular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katja Lund CliffDepartment of Clinical Biochemistry Aalborg University Hospital Aalborg Denmark.ORCID https://orcid.org/0009-0001-3250-8509
Dominic GuanzonTranslational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group, Frazer Institute, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland Brisbane Australia.ORCID https://orcid.org/0000-0001-7913-5749
Andrew LaiTranslational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group, Frazer Institute, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland Brisbane Australia.ORCID https://orcid.org/0000-0002-4424-8767
Katherin Scholz-RomeroTranslational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group, Frazer Institute, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland Brisbane Australia.
Gunna ChristiansenDepartment of Health Science and Technology Aalborg University Aalborg Denmark.ORCID https://orcid.org/0000-0003-0540-1367
Aase HandbergDepartment of Clinical Biochemistry Aalborg University Hospital Aalborg Denmark.ORCID https://orcid.org/0000-0001-5719-203X
Carlos SalomonTranslational Extracellular Vesicles in Obstetrics and Gynae-Oncology Group, Frazer Institute, Faculty of Health, Medicine and Behavioural Sciences The University of Queensland Brisbane Australia.ORCID https://orcid.org/0000-0003-4474-0046
Maiken MellergaardDepartment of Clinical Biochemistry Aalborg University Hospital Aalborg Denmark.ORCID https://orcid.org/0000-0001-5854-1086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the worldwide leading cause of liver-related mortality with a prevalence of 75% among individuals with obesity and lacking screenings tools. Extracellular vesicles (EVs)-based microRNAs (miRNAs) have emerged as promising biomarkers with important roles in the pathogenesis of MASLD. This study aimed to characterize EV-based miRNA profiles in individuals with obesity and MASLD before and during weight loss intervention. Small RNA sequencing was used to profile EV-miRNAs from plasma across three groups: individuals with obesity and MASLD (

Indexed as

biomarkersEVsMASLDmiRNANAFLDobesity

Identifiers

PMID42620933
PMCPMC13487377

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.