Evidence map›Paper›PMID 42621047›Full record

ArticleThe journal of allergy and clinical immunology. Global2026

Microneedles for allergy skin testing: Comprehensive analysis of agreement, accuracy, and pain.

Manaporn Sirichuwong, Kantima Kanchanapoomi, Surapon Piboonpocanun, Witchaya Srisuwatchari, Punchama Pacharn, Yossawat Rayanasukha, Nattaporn Paetanom, Kittipong Tantisantisom, Sattra Thongma, Supone Manakasettharn and 1 more

Abstract read
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Manaporn SirichuwongDivision of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Kantima KanchanapoomiDivision of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Surapon PiboonpocanunInstitute of Molecular Biosciences, Mahidol University, Salaya Campus, Nakhonpathom, Thailand.
Witchaya SrisuwatchariDivision of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Punchama PacharnDivision of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Yossawat RayanasukhaNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Nattaporn PaetanomNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Kittipong TantisantisomNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Sattra ThongmaNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Supone ManakasettharnNational Nanotechnology Center (NANOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand.
Orathai JirapongsananurukDivision of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The skin prick test (SPT) is a standard method for identifying allergic sensitization. However, pain and needle phobia often compromise pediatric compliance. Microneedle devices offer a minimally invasive alternative to conventional lancets. Objective: We evaluated the agreement, diagnostic accuracy, and patient tolerability of a novel microneedle compared to a lancet for SPT. Methods: Subjects with allergic rhinitis underwent SPT using both devices with Results: Of 150 subjects (aged 8-60 years), 53.3% were sensitized to Conclusion: The microneedle demonstrates high diagnostic performance and good concordance with the standard lancet while significantly reducing pain, thus supporting its utility in pediatric and needle-averse populations.

Indexed as

Accuracyconcordancediagnostic testlancetmicroneedlepainsensitivityskin prick testspecificityvisual analog scale

Identifiers

PMID42621047
PMCPMC13486330

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.