Evidence map›Paper›PMID 42621349›Full record

ArticleAJPM focus2026

Cardiovascular Health of U.S. Early Adolescents Assessed by the Life's Essential 8 Metric.

Jason M Nagata, Christiane K Helmer, Isaac Frimpong, Alexander W Heuer, Keira Beltran Murillo, Nathan D Nguyen, Oliver H Huang, Abubakr A Al-Shoaibi, Kelley Pettee Gabriel, Erin E Dooley and 2 more

Abstract read
In one paragraph

Article in AJPM focus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jason M NagataDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Christiane K HelmerDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Isaac FrimpongDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Alexander W HeuerDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Keira Beltran MurilloDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Nathan D NguyenDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Oliver H HuangDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Abubakr A Al-ShoaibiDepartment of Pediatrics, University of California, San Francisco, San Francisco, California.
Kelley Pettee GabrielDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Erin E DooleyDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.
Fiona C BakerCenter for Health Sciences, SRI International, Menlo Park, California.
Holly C GoodingDivision of General Pediatrics and Adolescent Medicine, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia.

Funding

ABCD-USA Consortium: Coordinating CenterU24DA041147 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDRA A BROWN, TERRY L. JERNIGAN · 2015 to 2026
$54.7M
ABCD-USA Consortium: Data Analysis, Informatics and Resource CenterU24DA041123 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANDERS M DALE · 2015 to 2026
$51.5M
Adolescent Substance Use Initiation: Disentangling neurocognitive risks from consequences using longitudinal and genetically-informed methodsU01DA041120 · NIDA · UNIVERSITY OF MINNESOTA · PI Monica Luciana, Sylia Wilson · 2015 to 2026
$34.5M
ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Prospective Research Studies of Maturation (PRISM)- Research ProjectU01DA041134 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI ERIN MCGLADE, PERRY FRANKLIN RENSHAW · 2015 to 2026
$29.2M
ABCD-USA CONSORTIUM: RESEARCH PROJECTU01DA041048 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Megan Marie Herting, ELIZABETH R SOWELL · 2015 to 2026
$28.7M
ABCD-USA Consortium: Research ProjectU01DA041106 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mary M Heitzeg, Chandra Sekhar Sripada · 2015 to 2026
$24.9M
FIU-ABCD: Pathways and Mechanisms to Addiction in the Latino Youth of South FloridaU01DA041156 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI Raul Gonzalez, Angela R Laird · 2015 to 2026
$22.8M
ABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3M
ABCD-USA: NYC Research ProjectU01DA041174 · NIDA · YALE UNIVERSITY · PI Arielle Ryan Baskin-Sommers, Betty J Casey · 2015 to 2026
$19.7M
Adolescent Brain Cognitive Development (ABCD) Prospective Research in Studies of Maturation (PRISM) ConsortiumU01DA041117 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LINDA CHANG, THOMAS M ERNST · 2015 to 2026
$19.5M
ABCD-USA Consortium:Research ProjectU01DA041028 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUNCAN B. CLARK, BEATRIZ LUNA · 2015 to 2026
$13.9M
NHLBI NIH HHS K08 HL159350NIDA NIH HHS R01 DA064134NIDA NIH HHS U01 DA041022NIDA NIH HHS U01 DA041025NIDA NIH HHS U01 DA041028NIDA NIH HHS U01 DA041048NIDA NIH HHS U01 DA041089NIDA NIH HHS U01 DA041093NIDA NIH HHS U01 DA041106NIDA NIH HHS U01 DA041117NIDA NIH HHS U01 DA041120NIDA NIH HHS U01 DA041134NIDA NIH HHS U01 DA041148NIDA NIH HHS U01 DA041156NIDA NIH HHS U01 DA041174NIDA NIH HHS U24 DA041123NIDA NIH HHS U24 DA041147NIMH NIH HHS RF1 MH135492
6 · The paper itself

Abstract

Introduction: This study aimed to characterize cardiovascular health among U.S. early adolescents using the American Heart Association's Life's Essential 8 metric in a large national cohort. Methods: A cross-sectional analysis of children aged 10-13 years in the Adolescent Brain Cognitive Development Study was conducted, primarily using data from the Year 2 follow-up (2018-2020), with supplemental Year 3 (2019-2021) data to improve completeness of cardiometabolic measures. Life's Essential 8 behavioral factors scores (diet, physical activity, nicotine exposure, sleep) and health factors scores (BMI, blood pressure, blood glucose, blood lipids) as well as overall Life's Essential 8 scores were calculated. Descriptive statistics were generated, and sex (assigned at birth) differences were assessed using Mann-Whitney Results: Among participants with complete Life's Essential 8 data ( Conclusions: In this national sample of early adolescents, fewer than half demonstrated high cardiovascular health on the basis of Life's Essential 8, and optimal cardiovascular health was rare. Poor diet and low physical activity were prominent contributors to suboptimal cardiovascular health. These findings highlight early adolescence as a critical window for interventions to improve long-term cardiovascular health.

Indexed as

cardiometaboliclifestylepreventionTeenyouth

Identifiers

PMID42621349
PMCPMC13487616

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.