ReviewInternational journal of preventive medicine2026
Diet during Pregnancy and Allergy Onset in the Childhood: A Systematic Literature Review and Meta-Analysis.
Review in International journal of preventive medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Maternal diet during pregnancy may influence childhood allergy risk. Our objective is to study the relationship between maternal diet during pregnancy and childhood's allergy onset. Methods: We systematically search SCOPUS and PubMed (2014 to 2024) for randomized controlled trials (RCTs), case control, and cohorts investigating maternal diet during pregnancy and childhood allergy outcomes. The study protocol was registered in the PROSPERO (CRD42024570531). The evidence was critically appraised using Newcastle Ottawa Scale for case-control and cohort studies and Revised Cochrane risk of bias for cluster randomized trials (RoB2) tool for RCTs by two independent reviewers. Random-effects meta-analyses were performed to pool effect estimates, and heterogeneity was assessed using the I Results: A total of 41 studies (37 cohorts, 1 case-control, and 3 RCTs) were analyzed. Meta-analyses suggest that maternal egg intake during pregnancy has a protective role on childhood eczema (OR: 0.51; 95% CI: 0.32, 0.80) and food allergy (OR: 0.60, 95% CI: 0.38, 0.96), and vitamin D has a negative association with childhood rhinitis (OR: 0.86; 95% CI: 0.76, 0.97). No significant association was found between maternal vitamin D intake on childhood asthma and fish oil supplementation on childhood hay fever and asthma. Variability in methodology, dietary assessment methods, and follow-up duration contributed to heterogeneity and becomes the limitation in our study. Conclusions: specific maternal diet patterns, such as egg and vitamin D consumption during pregnancy, may have help preventing childhood eczema, food allergy, and rhinitis. Further RCTs are needed to explore the effects of other dietary components on allergy outcomes.
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