Evidence map›Paper›PMID 42630350›Full record

ArticleFrontiers in cellular and infection microbiology2026

Cafestol and kahweol: coffee diterpenes with trypanocidal activity and cardioprotective effects.

Juliana Magalhães Chaves Barbosa, Bruna Macedo Simões, Fábio Junior Moreira Novaes, Maria Alice Esteves da Silva, Patrícia Bernardino da Silva, Francisco Radler de Aquino Neto, Claudia Moraes de Rezende, Kelly Salomão, Tatiana Galvão de Melo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juliana Magalhães Chaves BarbosaLaboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Bruna Macedo SimõesLaboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Fábio Junior Moreira NovaesLaboratório de Química Analítica - LAQUA, Departamento de Química, Universidade Federal de Viçosa, Viçosa, MG, Brazil.
Maria Alice Esteves da SilvaLaboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Patrícia Bernardino da SilvaLaboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Francisco Radler de Aquino NetoLADETEC, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro RJ, Brazil.
Claudia Moraes de RezendeLaboratório de Análise de Aromas, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Kelly SalomãoLaboratório de Biologia Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.
Tatiana Galvão de MeloLaboratório de Ultraestrutura Celular, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chagas disease (CD), caused by Methods: To investigate the trypanocidal potential of Results: The results demonstrated that the combination of Discussion: Moreover, the

Indexed as

Cardiotonic AgentsCoffeaDiterpenesDiterpenes, KauraneTrypanocidal AgentsTrypanosoma cruziAnimalsChagas DiseaseCoffeeHumansMicePlant ExtractscafestolCardiotonic AgentsCoffeeDiterpenesDiterpenes, KauranekahweolPlant ExtractsTrypanocidal Agentscafestol and kahweolChagas diseaseCoffea arabica L.diterpenesTrypanosoma cruzi

Identifiers

PMID42630350
PMCPMC13493510

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.