Evidence map›Paper›PMID 42630808›Full record

ArticleKidney international reports2026

Dual Burden of Kidney Disease and Cognitive Impairment in the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia-Cohort.

Aradhana Nayak, Sandhya G, Vamsi K Yenamandra, Jonas S Sundarakumar, Latha Diwakar, Thomas Gregor Issac, Swaminathan Sundararaman

Abstract read
In one paragraph

Article in Kidney international reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aradhana NayakAll India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Sandhya GCentre for Brain Research, Indian Institute of Science, Bengaluru, Karnataka, India.
Vamsi K YenamandraDepartment of Nephrology, Tata-IISc Medical School, Indian Institute of Science, Bengaluru, Karnataka, India.
Jonas S SundarakumarCentre for Brain Research, Indian Institute of Science, Bengaluru, Karnataka, India.
Latha DiwakarCentre for Brain Research, Indian Institute of Science, Bengaluru, Karnataka, India.
Thomas Gregor IssacCentre for Brain Research, Indian Institute of Science, Bengaluru, Karnataka, India.
Swaminathan SundararamanDepartment of Nephrology, Tata-IISc Medical School, Indian Institute of Science, Bengaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic kidney disease (CKD) and cognitive impairment are being increasingly recognized as major public health challenges in aging populations, yet their interrelationship remains underexplored in India. Methods: Data from Longitudinal Aging Study in India- Diagnostic Assessment of Dementia (LASI-DAD) cohort was analyzed. Estimated glomerular filtration rate (eGFR) was estimated using serum creatinine, cystatin C, and combined CKD-Epidemiology Collaboration (CKD-EPI) equations. Cognitive performance was assessed using Hindi Mental State Examination (HMSE) and domain-specific cognitive tests. Results: The prevalence of eGFR <60 ml/min per 1.73 m Conclusion: No significant association between eGFR and cognition was found in the LASI-DAD cohort. High prevalence of reduced eGFR and cognitive impairment may be attributed to age, modifiable risk factors, and region-specific differences, highlighting the need for further longitudinal research in low- and middle-income countries (LMICs).

Indexed as

chronic kidney diseasecognitive impairmentcreatinine to cystatin C ratiokidney-brain axisLASI-DAD

Identifiers

PMID42630808
PMCPMC13495598

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.