Evidence map›Paper›PMID 42630964›Full record

ArticleAlzheimer's & dementia. Behavior & socioeconomics of aging2026

Unfavorable Social Determinants of Health Are Associated with Lower Cognitive Performance in Non-Hispanic Black Men - The HABS-HD Study.

Raymond Jones, Cellas A Hayes, Michael J Hankes, Roland J Thorpe, Health and Aging Brain Study (HABS-HD) Study Team

Abstract read
In one paragraph

Article in Alzheimer's & dementia. Behavior & socioeconomics of aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raymond JonesDepartment of Medicine, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL, USA.ORCID 0000-0001-9241-2309
Cellas A HayesStanford University School of Medicine Department of Epidemiology and Population Health. 1701 Page Mill Road, Palo Alto, California 94304, United States.
Michael J HankesCenter for Exercise Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Roland J ThorpeProgram for Research on Men's Health, Johns Hopkins Center for Health Disparities Solutions, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. 624 N. Broadway, Suite 441 Baltimore, Maryland 21205, United States.
Health and Aging Brain Study (HABS-HD) Study Team

Funding

The Health & Aging Brain Study - Health Disparities (HABS-HD)U19AG078109 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI LEIGH A JOHNSON, Sid E O'Bryant · 2022 to 2026
$181.1M
Health and Aging Brain among Latino Elders (HABLE-AT(N)) StudyR01AG058533 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI JOHNSON, LEIGH A, O'BRYANT, SID E · 2020 to 2025
$45.4M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican AmericansR01AG054073 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI O'BRYANT, SID E, TOGA, ARTHUR W · 2017 to 2021
$12.6M
The Johns Hopkins Alzheimer's Disease Resource Center for Minority Aging Research - Research Ed ComponentP30AG059298 · NIA · JOHNS HOPKINS UNIVERSITY · PI Quincy Miles Samus · 2018 to 2026
$7.1M
Stress and Mortality Among Black MenK02AG059140 · NIA · JOHNS HOPKINS UNIVERSITY · PI THORPE, ROLAND J. · 2018 to 2022
$1.1M
A Pilot Trial of High-Intensity Exercise to Combat Vascular and Cognitive Dysfunction in Older Adults with HIV.K01AG086063 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Raymond Jones · 2024 to 2026
$378k
NIA NIH HHS K01 AG086063NIA NIH HHS K02 AG059140NIA NIH HHS P30 AG059298NIA NIH HHS R01 AG054073NIA NIH HHS R01 AG058533NIA NIH HHS U19 AG078109NIBIB NIH HHS P41 EB015922
6 · The paper itself

Abstract

Introduction: Non-Hispanic Black (NHB) men experience disproportionate exposure to adverse social determinants of health (SDoH). The cumulative impact on cardiometabolic risk factors, cognitive and neuroimaging outcomes is not well understood. Methods: We analyzed data from 460 NHB men. Cumulative SDoH index spanning multiple domains was examined both categorically and continuously. Regression models were performed to estimate associations of cumulative SDoH index with cardiometabolic risk factors, cognitive performance, and neuroimaging biomarkers. Results: Higher cumulative SDoH burden was associated with a greater prevalence of diabetes, tobacco use, and cognitive impairment. Cumulative SDoH was not associated with neuroimaging biomarkers (p>0.05). Greater cumulative SDoH burden showed an independent association with poor memory, executive function, and processing speed ( Discussion: Our findings identified social and structural factors that were linked to cardiometabolic risk and cognitive health among NHB men; however, cumulative SDoH burden was not independently associated with white matter hyperintensities or hippocampal volume.

Indexed as

brain healthCognitive performancedementiadeterminants of health

Identifiers

PMID42630964
PMCPMC13496262

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.