Evidence map›Paper›PMID 42634098›Full record

Trial reportObesity (Silver Spring, Md.)2026

Weight Loss Improves Predicted 10-Year MACE and Type 2 Diabetes Risk, but Benefits Partially Rebound at 1 Year.

Abdelrahman M Elshakankiry, Gary R Hunter, Cátia Martins, Gordon Fisher, W Timothy Garvey, Carrie R Howell

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00067873 (Exercise Training in Obesity-prone Black and White Women), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00067873 nacompletednot on this map

Exercise Training in Obesity-prone Black and White Women

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2000 to 2007Enrolled231ConditionsObesityArmsDiet, Aerobic exercise, Resistance exercise
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdelrahman M ElshakankiryDepartment of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0003-4950-9804
Gary R HunterDepartment of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-5015-242X
Cátia MartinsDepartment of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-4560-0013
Gordon FisherDepartment of Human Studies, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-9191-3774
W Timothy GarveyDepartment of Nutrition Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0003-0822-0860
Carrie R HowellDepartment of Medicine, Division of Internal General Medicine and Population Science, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID https://orcid.org/0000-0002-6554-6237

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
Zevalin Radioimmunotherapy Using a Modified TreatmentM01RR000032 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RICH, ROBERT R. · 1985 to 2008
$23.6M
EXERCISE TRAINING IN OBESITY-PRONE BLACK AND WHITE WOMENR01DK049779 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOWER, BARBARA A, HUNTER, GARY R · 1995 to 2013
$4.4M
LONG TERM FOLLOW UP OF POST OBESE BLACK AND WHITE WOMENR01DK051684 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GOWER, BARBARA A · 1997 to 2008
$3.3M
NCRR NIH HHS M01 RR000032NIDDK NIH HHS P30 DK056336NIDDK NIH HHS R01 DK049779NIDDK NIH HHS R01 DK051684NIH HHS M01-RR00032NIH HHS P30-DK56336NIH HHS R01 DK 49779NIH HHS R01 DK51684
6 · The paper itself

Abstract

objectiveThis study aimed to quantify changes in predicted 10-year risk for major adverse cardiovascular events (MACE) and type 2 diabetes (T2D) across weight loss, post-weight loss (Post-WL), and 1-year follow-up and to determine whether trajectories varied by exercise modality.

methodsSedentary women with overweight (21-49 years) were randomized to Diet+Aerobic, Diet+Resistance, or Diet-only and completed an 800 kcal/day diet until BMI < 25 kg m

resultsAmong 221 women (115 African American), mean BMI decreased from 28.3 to 23.9 kg m

conclusionsWeight loss reduced MACE and T2D risks, but both rebounded with weight regain. Resistance exercise may be beneficial in weight loss interventions to prevent progression to T2D.

trial registrationClinicalTrials.gov identifier: NCT00067873.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2OverweightWeight LossAdultBody Mass IndexDiet, ReducingExerciseFemaleFollow-Up StudiesHumansMiddle AgedObesityResistance TrainingRisk Factorscardiometabolic riskresistance exercisetype 2 diabetesweight lossweight regain

Identifiers

PMID42634098
PMCPMC13615421

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.