Evidence map›Paper›PMID 42634760›Full record

ArticleCureus2026

Recurrent Tumor-Induced Osteomalacia After Surgical Resection: A Case Report Demonstrating Successful Treatment With Burosumab.

Carla Nicolau, Miguel Bigotte Vieira, Joana Dinis Melo, Caixia Zhu, Lino Fonseca, João Calado, Ana Carina Ferreira, Cristina Jorge, Anibal Ferreira

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carla NicolauNephrology, Unidade Local de Saúde de São José, Lisbon, PRT.
Miguel Bigotte VieiraNephrology, Unidade Local de Saúde de São José, Lisbon, PRT.
Joana Dinis MeloRheumatology, Unidade Local de Saúde de São José, Lisbon, PRT.
Caixia ZhuRadiology, Unidade Local de Saúde de São José, Lisbon, PRT.
Lino FonsecaNeurosurgery, Unidade Local de Saúde de São José, Lisbon, PRT.
João CaladoNephrology, Unidade Local de Saúde de São José, Lisbon, PRT.
Ana Carina FerreiraNephrology, Hospital Curry Cabral, Centro Hospitalar Universitário de Lisboa Central (EPE), Lisbon, PRT.
Cristina JorgeNephrology, Unidade Local de Saúde de São José, Lisbon, PRT.
Anibal FerreiraNephrology, Unidade Local de Saúde de São José, Lisbon, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome in which a mesenchymal tumor secretes fibroblast growth factor 23 (FGF-23), causing renal phosphate wasting and osteomalacia. A 62-year-old woman was referred to our hospital with a two-year history of progressive muscle weakness and generalized bone pain. The patient was nonambulatory and required a wheelchair for mobility. Laboratory evaluation revealed hypophosphatemia and low serum 1,25-dihydroxyvitamin D levels. Further investigation of the hypophosphatemia demonstrated an elevated fractional excretion of phosphate (FeP) and increased serum FGF-23 levels. Genetic testing was negative. A

Indexed as

burosumabfibroblast growth factor-23hypophosphatemiaosteomalaciatumor-induced osteomalacia

Identifiers

PMID42634760
PMCPMC13500089

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.