Evidence map›Paper›PMID 42634827›Full record

ArticleVeterinary world2026

Metabolomic profiling and dual antimicrobial and antioxidant activities of <em>Coleus scutellarioides</em> (L.) Benth. leaves against <em>Neisseria gonorrhoeae</em> and <em>Candida albicans</em>: An <em>in vitro</em> study.

Marni Br Karo, Farida Mentalina Simanjuntak, Tetty Rina Aritonang, Desweri Muhareni, Dea Dea, Yola Maharani

Abstract read
In one paragraph

Article in Veterinary world, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marni Br KaroSekolah Tinggi Ilmu Kesehatan Medistra Indonesia, Bekasi 17113, Indonesia.
Farida Mentalina SimanjuntakSekolah Tinggi Ilmu Kesehatan Medistra Indonesia, Bekasi 17113, Indonesia.
Tetty Rina AritonangSekolah Tinggi Ilmu Kesehatan Medistra Indonesia, Bekasi 17113, Indonesia.
Desweri MuhareniSekolah Tinggi Ilmu Kesehatan Medistra Indonesia, Bekasi 17113, Indonesia.
Dea DeaUndergraduate Study Program of Pharmacy, Sekolah Tinggi Ilmu Kesehatan Medistra Indonesia, Bekasi 17113, Indonesia.
Yola MaharaniUndergraduate Study Program of Midwifery, Sekolah Tinggi Ilmu Kesehatan Medistra Indonesia, Bekasi 17113, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: The increasing antimicrobial resistance of Materials and Methods: Leaves were extracted by maceration using 96% ethanol. Untargeted metabolomic profiling was performed using LC-HRMS with an Orbitrap Q Exactive Plus system. Antimicrobial activity against Results: LC-HRMS detected 243 metabolites, including 20 major bioactive compounds belonging predominantly to flavonoids, diterpenoids, terpenoids, phenolic acids, coumarins, fatty acids, and alkaloids. Major constituents included apigenin, kaempferol, caffeic acid, lupeol, triptolide, carnosol, kahweol, nootkatone, and betaine. The extract demonstrated fungicidal activity against Conclusion: Ethanol extracts of Miana leaves contain diverse bioactive metabolites that confer dual antimicrobial activity against

Indexed as

antioxidant activityCandida albicansColeus scutellarioidesgenital infectionsLC–HRMSmetabolomicsNeisseria gonorrhoeaephytochemicals

Identifiers

PMID42634827
PMCPMC13500132

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.