Evidence map›Paper›PMID 42635393›Full record

ArticleEuropean journal of immunology2026

IL-9 Is Essential for ILC2-Mediated but Not Th2- and Th17-Cell-Mediated Allergic Airway Inflammation in Mice.

Nikolaos D Sidiropoulos, Franziska Ampenberger, Christoph Schlapbach, Christoph Schneider, Manfred Kopf

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nikolaos D SidiropoulosInstitute of Molecular Health Sciences, ETH Zürich, Zürich, Switzerland.ORCID 0000-0003-3257-3455
Franziska AmpenbergerInstitute of Molecular Health Sciences, ETH Zürich, Zürich, Switzerland.
Christoph SchlapbachDepartment of Dermatology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.ORCID 0000-0003-0258-1243
Christoph SchneiderInstitute of Physiology, University of Zürich, Zürich, Switzerland.ORCID 0000-0002-0452-2960
Manfred KopfInstitute of Molecular Health Sciences, ETH Zürich, Zürich, Switzerland.ORCID 0000-0002-0628-7140

Funding

ETH Zürich Project SKINTEGRITY.CHSwiss National Science Foundation, Eccellenza 194216
6 · The paper itself

Abstract

Interleukin-9 (IL-9) has primarily been associated with type 2 immunity in health and disease. While its impact on innate lymphoid cells (ILC2s) is well known, the cellular targets and mechanisms underlying type 2 immunity remain incompletely understood. In this study, we report the generation of a mouse-specific anti-IL-9 receptor (IL-9R) antibody, enabling us to accurately map IL-9R protein expression across various immune cell types. In naïve mice, IL-9R was detectable in ILC2s, marginal zone B cells, and B1b cells. In allergic lung inflammation, a subset of CD4

Indexed as

AsthmaInterleukin-9LymphocytesTh17 CellsTh2 CellsAnimalsDisease Models, AnimalFemaleImmunity, InnateLungMiceMice, Inbred C57BLMice, KnockoutPapainPneumoniaReceptors, Interleukin-9Interleukin-9PapainReceptors, Interleukin-9HDM‐induced asthmaIL‐9IL‐9R‐specific antibodyILC2papain

Identifiers

PMID42635393
PMCPMC13501938

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.