ArticleClinical research in cardiology : official journal of the German Cardiac Society2026
Quantifying the inclusion of cardiovascular research into clinical guidelines.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe number of cardiovascular research articles is growing rapidly, but the subsequent incorporation into newer guidelines remains uncertain. We aimed to quantify the proportion of topic-relevant literature published between consecutive European Society of Cardiology (ESC) guideline editions that was cited in the later edition.
methodsUsing PubMed Medical Subject Heading (MeSH) searches and OpenAlex citation graphs, we identified all publications published between two ESC guideline editions across eight topics. We quantified the proportion of inter-guideline publications that were cited in the subsequent guideline.
resultsAcross the eight topics, a mean of 2.2% (SD = 2.0) of inter-guideline publications were directly cited in the successive guideline. Clinical trials were more frequently cited than non-clinical trial publications (8.5% [SD = 6.8] vs 2.0% [SD = 2.0]) in a topic-adjusted logistic regression; the odds were roughly fivefold higher (OR 5.45, 95% CI 4.87-6.10).
conclusionsESC guidelines cite a small proportion of the cardiovascular literature published since their preceding edition, drawing disproportionately on clinical trials.
Indexed as
Identifiers
42635753What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.