Evidence map›Paper›PMID 42636212›Full record

ArticlePLoS neglected tropical diseases2026

Vector competence of temperate and tropical mosquito species for Babanki virus.

Mathilde Ban, Virginie Geolier, Emeline Perthame, Elisabeth Ferquel, Martin Faye, Moussa Moise Diagne, El Hadji Ndiaye, Gamou Fall, Mawlouth Diallo, Dimitri Lavillette and 1 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mathilde BanGlobal Health Department, Environment and Infectious Risk Unit, Institut Pasteur, Université Paris Cité, Paris, France.
Virginie GeolierGlobal Health Department, Environment and Infectious Risk Unit, Institut Pasteur, Université Paris Cité, Paris, France.
Emeline PerthameBioinformatic and biostatistics Hub, Institut Pasteur, Université Paris Cité, Paris, France.
Elisabeth FerquelGlobal Health Department, Environment and Infectious Risk Unit, Institut Pasteur, Université Paris Cité, Paris, France.
Martin FayeVirology Unit, Institut Pasteur de Dakar, Dakar, Senegal.
Moussa Moise DiagneVirology Unit, Institut Pasteur de Dakar, Dakar, Senegal.
El Hadji NdiayeMedical Zoology Unit, Institut Pasteur de Dakar, Dakar, Senegal.
Gamou FallVirology Unit, Institut Pasteur de Dakar, Dakar, Senegal.
Mawlouth DialloMedical Zoology Unit, Institut Pasteur de Dakar, Dakar, Senegal.
Dimitri LavilletteInternational Infectiology Research Center, HepVir, Inserm U1111-Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université Lyon, Lyon, France.
Valérie ChoumetGlobal Health Department, Environment and Infectious Risk Unit, Institut Pasteur, Université Paris Cité, Paris, France.ORCID https://orcid.org/0000-0003-4714-1006

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Babanki virus (BBKV), an alphavirus belonging to the Western Equine Encephalitis antigenic complex, was first isolated from Mansonia africana mosquitoes in 1969 but remains poorly characterized. Transmitted to humans and animals through the bite of an infectious female mosquito, it is associated with febrile illness, rash, and arthritis, similarly to its close relative Sindbis virus. No specific treatment or vaccine is currently available. Here, we experimentally assessed the vector competence of mosquito species from tropical and temperate regions under ecologically relevant temperature conditions. Using a BBKV molecular clone, individual midguts, salivary glands, legs, and saliva samples were collected at different time points to assess infection, dissemination, and transmission dynamics in Aedes (Aedes albopictus from Nice and Réunion Island, and Aedes aegypti) and Culex (Culex pipiens molestus from Paris and Culex quinquefasciatus) mosquitoes. We show that BBKV efficiently infects and disseminates in all tested species, with Aedes mosquitoes exhibiting higher infection rates (>70%) compared to Culex species. Importantly, infectious viral particles were detected in mosquito saliva, confirming transmission potential. Viral replication persisted over time and was supported by both RNA quantification and infectious virus titration. Overall, our results show that multiple mosquito species from both temperate and tropical regions are competent vectors for BBKV, highlighting a significant emergence potential.

Indexed as

AedesAlphavirusCulexMosquito VectorsAlphavirus InfectionsAnimalsFemaleSalivaTemperatureTropical Climate

Identifiers

PMID42636212
PMCPMC13552956

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.